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Cortisol, Socioeconomic Status, and Genetic Influences on Cognitive Development

Description: PUBLIC HEALTH RELEVANCE: How do disadvantaged social contexts "get under the skin" to influence cognitive development in childhood? Using a diverse sample of twins in grades 3-5, this project will examine cortisol reactivity, cortisol diurnal rhythm, and chronic cortisol accumulation as biological substrates of socioeconomic disparities in cognitive development. Results will inform interventions and policies designed to ameliorate inequalities in cognition and academic achievement and maximize children's potentials for healthy development and learning.
Funding type: research
Funder scheme: R01
Start date: 2016-01-01
End date: 2021-12-31
Investigator: ELLIOT MAX TUCKER-DROB
Institution: UNIVERSITY OF TEXAS AT AUSTIN
Funded outputs count: 82
Funder award ID: R01HD083613
OpenAlex ID: G301826101
Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification
2025 · Deniz Fraemke, Yayouk E. Willems, et al. · Psychological Science · 4
Stability of Aging- and Cognition-Related Methylation Profile Scores Across Two Waves in Children and Adolescents
2025 · Abby J deSteiguer, Laurel Raffington, et al. · Child Development · 9
Differences in polygenic associations with educational attainment between West and East Germany before and after reunification
2024 · D. Fraemke, Y.E. Willems, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Stability of DNA-Methylation Profiles of Biological Aging in Children and Adolescents
2023 · Abby J. deSteiguer, Laurel Raffington, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 7
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Salivary Epigenetic Measures of Body Mass Index and Social Determinants of Health Across Childhood and Adolescence
2023 · Laurel Raffington, Lisa Schneper, et al. · Archives of Pediatrics and Adolescent Medicine · 23
Associations of DNA-Methylation Measures of Biological Aging With Social Disparities in Child and Adolescent Mental Health
2023 · Laurel Raffington, Peter T. Tanksley, et al. · Clinical Psychological Science · 24
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Measuring the long arm of childhood in real-time: Epigenetic predictors of BMI and social determinants of health across childhood and adolescence
2023 · Laurel Raffington, Lisa Schneper, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Associations of Socioeconomic Disparities With Buccal DNA-Methylation Measures Of Biological Aging
2022 · L. Raffington, T. Schwaba, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Socially Stratified Epigenetic Profiles Are Associated With Cognitive Functioning in Children and Adolescents
2022 · Laurel Raffington, Peter T. Tanksley, et al. · Psychological Science · 41
A Mixed‐Methods Approach to Refining and Measuring the Construct of Positive Risk‐Taking in Adolescence
2022 · Megan W. Patterson, Lilla Pivnick, et al. · Journal of Research on Adolescence · 17
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Genetic variance in conscientiousness relates to youth psychopathology beyond executive functions.
2022 · Allison N. Shields, Margherita Malanchini, et al. · Journal of Psychopathology and Clinical Science · 3
Transcriptome-wide and stratified genomic structural equation modeling identify neurobiological pathways shared across diverse cognitive traits
2022 · Andrew D. Grotzinger, Javier de la Fuente, et al. · Nature Communications · 32
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An in-laboratory stressor reveals unique genetic variation in child cortisol output.
2022 · Laurel Raffington, Margherita Malanchini, et al. · Developmental Psychology · 7
Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities
2022 · Travis T. Mallard, Richard Karlsson Linnér, et al. · Cell Genomics · 98
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Genetic associations with learning over 100 days of practice
2022 · Cherry Youn, Andrew D. Grotzinger, et al. · npj Science of Learning · 2
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Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis
2022 · Andrew D. Grotzinger, Travis T. Mallard, et al. · Nature Genetics · 333
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Blood-based epigenome-wide analyses of cognitive abilities
2022 · Daniel L. McCartney, Robert F. Hillary, et al. · Genome biology · 55
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Geographic variation in personality is associated with fertility across the United States
2021 · Eleanor J. Junkins, Joseph E. Potter, et al. · Personality Science · 7
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Modeling Interaction and Dispersion Effects in the Analysis of Gene-by-Environment Interaction
2021 · Benjamin W. Domingue, Klint Kanopka, et al. · Behavior Genetics · 23
Socially stratified DNA-methylation profiles are associated with disparities in child and adolescent mental health
2021 · L. Raffington, P. Tanksley, et al. · medRxiv · 3
Genetic and Environmental Factors of Non-Ability-Based Confidence
2021 · Randi L. Vogt, Anqing Zheng, et al. · Social Psychological and Personality Science · 7
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
2021 · Richard Karlsson Linnér, Travis T. Mallard, et al. · Nature Neuroscience · 317
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The relationship between executive function, processing speed, and attention‐deficit hyperactivity disorder in middle childhood
2021 · Aditi Sabhlok, Margherita Malanchini, et al. · Developmental Science · 18
Resource profile and user guide of the Polygenic Index Repository
2021 · Joel Becker, Casper A. P. Burik, et al. · Nature Human Behaviour · 173
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Socioeconomic Disadvantage and the Pace of Biological Aging in Children
2021 · Laurel Raffington, Daniel W. Belsky, et al. · PEDIATRICS · 140
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