Coordinated patterning of brain regions
Description: Project Narrative Drosophila, with its genetic amenability and small brain size, yet sophisticated behavior, is a powerful model system to study how photoreceptor neurons that are stochastically specified communicate their decision to their downstream targets to propagate their specific sensory information. Activity-dependent neural patterning is another powerful mean to coordinate patterning of different brain regions and we will study how waves of activity that we observe at a very specific time point during retinal development are generated and what role they play. The principles deduced from this project will be applicable to other neural systems in more complex organisms.
Funder: National Eye Institute
Funding type: research
Funder scheme: R01
Start date: 1999-09-01
End date: 2026-08-31
Investigator: CLAUDE DESPLAN (lead)
Institution: New York University
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Funded outputs count: 74
Funder award ID: R01EY013010
OpenAlex ID: G9000875555