Award

Role of gasdermin D in bone resorption

Description: This project will use genetic and pharmacological approaches to determine the role that gasdermin D plays in bone loss caused by inflammation, radiotherapy, and chemotherapy. Successfully execution of this project will have translational implications because findings from this research can be exploited to treat bone loss associated with pathological conditions.
Funding type: research
Funder scheme: R01
Start date: 2020-02-15
End date: 2025-01-31
Investigator: GABRIEL MBALAVIELE
Institution: WASHINGTON UNIVERSITY
Funded outputs count: 27
Funder award ID: R01AR076758
OpenAlex ID: G6799867860
2025 · Khushpreet Kaur, Yael Alippe, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2024 · Gaurav Swarnkar, Musarrat Naaz, et al. · Arthritis & Rheumatology · 4
2024 · Chun Wang, Khushpreet Kaur, et al. · eLife · 11
2024 · Gaurav Swarnkar, Nicholas P. Semenkovich, et al. · Proceedings of the National Academy of Sciences · 11
2024 · Chun Wang, Khushpreet Kaur, et al. · eLife · 1
2024 · Chun Wang, Khushpreet Kaur, et al. · eLife · 7
2023 · Kunjan Khanna, Hui Yan, et al. · Arthritis & Rheumatology · 11
2023 · Inés Muela-Zarzuela, Juan Miguel Suarez-Rivero, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6
2022 · Manoj Arra, Gaurav Swarnkar, et al. · eLife · 45
2022 · Jianqiu Xiao, Kai Sun, et al. · Journal of Translational Autoimmunity · 24
2021 · Chun Wang, Tong Yang, et al. · Science Immunology · 314
2021 · Alvaro González‐Dominguez, Raúl Montañez, et al. · EMBO Molecular Medicine · 31
2021 · Elizabeth Mitton‐Fitzgerald, Claudia M. Gohr, et al. · Arthritis & Rheumatology · 13
2021 · Chun Wang, Tong Yang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 15
2021 · José M. Navarro-Pando, Elísabet Alcocer-Gómez, et al. · Science Advances · 206
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