Developing Effective Approaches to Extend Hematopoietic Healthspan by Targeting Cell-Extrinsic and Cell-Intrinsic Alterations at Middle Age
Description: PROJECT NARRATIVE Aging is a complex process that contributes to reduced function and elevated risk of various diseases in tissues throughout the body, including the blood system. The impact of aging on human health is of increasing societal concern due to the worldwide increase in the age of our population. Our research is relevant to public health because it will provide new information that can be used to develop therapies to sustain a healthy and robust blood system during aging and reduce risk of diseases such as blood cancer, cardiovascular disease, and type 2 diabetes.
Funding type: research
Funder scheme: R01
Start date: 2018-08-01
End date: 2028-04-30
Investigator: JENNIFER JEAN TROWBRIDGE
Institution: JACKSON LABORATORY
Funded outputs count: 36
Funder award ID: R01DK118072
OpenAlex ID: G9000877051