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Vascular Barrier Leakage in Inflammation

Description: PROJECT NARRATIVE Vascular barrier breakdown is a hallmark of aberrant inflammation associated with trauma, infection, and cardiovascular diseases. There are currently no drugs that can effectively stop or prevent vascular leakage, owing to our incomplete understanding of its underlying mechanisms. We propose an in-depth investigation of the molecular and cellular reactions in the vascular wall during inflammation in hopes to identify new diagnostic or therapeutic targets for effective treatment of vascular inflammation.
Funding type: research
Funder scheme: R35
Start date: 2020-05-15
End date: 2027-04-30
Investigator: SARAH Y YUAN
Institution: UNIVERSITY OF SOUTH FLORIDA
Funded outputs count: 25
Funder award ID: R35HL150732
OpenAlex ID: G9000881206
2026 · Daria M. Konovalova, Madison D. Cooper, et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2
2025 · Luis Arteaga-Blanco, Maliheh Najari Beidokhti, et al. · Fluids and Barriers of the CNS · 4
2025 · Maliheh Najari Beidokhti, Nuria Villalba, et al. · GeroScience · 21
2024 · Danielle X. Shane, Daria M. Konovalova, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 10
2023 · Jerome W. Breslin, Sarah Y. Yuan · Methods in molecular biology · 3
2023 · Nuria Villalba, Yonggang Ma, et al. · Journal of Neuroinflammation · 76
2023 · Yonggang Ma, Scott S. Kemp, et al. · Immunology Letters · 22
2023 · Nuria Villalba, Yonggang Ma, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
2022 · Xiaoyuan Yang, Ethan Zheng, et al. · Journal of Extracellular Biology · 14
2022 · Xiaoyuan Yang, Victor Chatterjee, et al. · Shock · 18
2022 · Yonggang Ma, Xiaoyuan Yang, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 30
2021 · Nuria Villalba, Sheon Baby, et al. · Frontiers in Cell and Developmental Biology · 108
2021 · Xiaoyuan Yang, Ethan Zheng, et al. · Scientific Reports · 15
2021 · Victor Chatterjee, Xiaoyuan Yang, et al. · The FASEB Journal
2021 · Xiaoyuan (Sherry) Yang, Victor Chatterjee, et al. · The FASEB Journal
2020 · Xiaoyuan Yang, Victor Chatterjee, et al. · Frontiers in Cell and Developmental Biology · 39
2020 · Victor Chatterjee, Xiaoyuan Yang, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 73
2020 · Nuria Villalba, Sheon Baby, et al. · Journal of Neuroinflammation · 48
2020 · Yonggang Ma, Xiaoyuan Yang, et al. · American Journal of Respiratory Cell and Molecular Biology · 77
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