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Solar-Eclipse Computational Tools for Imaging Genetics

Description: This application will provide urgently needed analytical methods to support high-resolution imaging genetics network analyses with the focus on major neuropsychiatric disorders. SOLAR- Eclipse is an integrated suite of resources for genetic and epigenetic analyses such as heritability, pleiotropy, high-resolution genome-wide association (GWA) and Whole-Genome Analyses (WGA), gene expression, quantitative trait loci-linkage (QTL-L) and methylation analyses optimized for traits derived from structural and functional neuroimaging data.
Funding type: research
Funder scheme: R01
Start date: 2012-08-01
End date: 2026-07-31
Investigator: PETER V. KOCHUNOV
Institution: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
Subfield: Genetics
Funded outputs count: 406
Funder award ID: R01EB015611
OpenAlex ID: G6901818774
The circulating lipidome in severe obesity
2026 · Mohammad Yaser Anwar, Heather M. Highland, et al. · iScience · 4
Correction: Blood and neuronal extracellular vesicle mitochondrial disruptions in schizophrenia
2026 · A. Ankeeta, Ashutosh Tripathi, et al. · Neuropsychopharmacology
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A neural signature of sleep deprivation in the human brain
2026 · Zhenfu Wen, Edward F. Pace-Schott, et al. · Nature Communications
Brain aging patterns among nine neurological disorders: A case-control study
2026 · Chuang Liang, Godfrey Pearlson, et al. · PLoS Medicine
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Clinical, cellular, and genomic consequences of a population-enriched SETD1A missense variant
2026 · Seth Ament, Robert Lease, et al. · Research Square · 1
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The Regional Vulnerability Index (RVI) as a Neuroimaging-Based Biomarker for Autism: Associations with Likelihood, Cognition, and Longitudinal Social Outcomes
2026 · Antonio Pagán, Katherine E. Lawrence, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Cerebral cortical alterations in adolescent early-onset psychosis: a surface-based morphometry mega-analysis
2026 · Stener Nerland, Claudia Barth, et al. · Molecular Psychiatry · 2
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Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
2026 · Alicia Huerta-Chagoya, Joohyun Kim, et al. · The Lancet Diabetes & Endocrinology · 11
Alzheimer’s disease-like brain pattern biomarker: capturing risks and predicting disease onset
2026 · Peter Kochunov, Si Gao, et al. · Molecular Psychiatry · 1
Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium.
2026 · McCauley, Stephen R, van Rooij, Sanne J H, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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Distinct profiles of white matter diffusivity in obesity and bipolar disorders: An ENIGMA bipolar disorders study in 2166 individuals
2026 · Lorielle M. F. Dietze, Sean R. McWhinney, et al. · Psychological Medicine
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Shared genetic architecture of brain age gap across 30 cohorts worldwide
2025 · Vilte Baltramonaityte, Philippe Jawinski, et al. · medRxiv
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Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium
2025 · Jelle Lamsma, Adrian Raine, et al. · Molecular Psychiatry · 3
White Matter Microstructure Alterations in Social Anxiety Disorder: A Mega-Analysis Across Twelve Cohorts in the ENIGMA-Anxiety Working Group
2025 · Eline F. Roelofs, Nynke A. Groenewold, et al. · Biological Psychiatry Cognitive Neuroscience and Neuroimaging
An Orthogonal Semi-Nonnegative Matrix Factorization Method for Dynamic Functional Connectivity Analysis and Its Application to Schizophrenia
2025 · Xingyu He, Vince D. Calhoun, et al. · IEEE Journal of Biomedical and Health Informatics
Striatum volume and affective symptomatology are associated with sleep in schizophrenia
2025 · Alia R. Warner, Xiaoming Du, et al. · Journal of Psychiatric Research
Heritability and shared environmental effects of brain diseases in 12,040 extended families
2025 · Janna I. R. Dijkstra, Marc Hulsman, et al. · npj Dementia · 3
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Role of epigenetic markers in cardiovascular disease following hypertensive disorders of pregnancy
2025 · Kimiya Padidar, Shaun Brennecke, et al. · Epigenomics · 2
Family History of Substance Use and Stressful Life Events Impact Adolescent Maturation of Cerebral White Matter
2025 · Yizhou Ma, Ashley Acheson, et al. · Addiction Biology · 1
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st‐ DenseViT : A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks
2025 · Behnam Kazemivash, Pranav Suresh, et al. · Human Brain Mapping · 2
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Early-Life Exposure to Organic Chemical Pollutants as Assessed in Primary Teeth and Cardiometabolic Risk in Mexican American Children: A Pilot Study
2025 · Vidya S. Farook, Feroz Akhtar, et al. · International Journal of Environmental Research and Public Health · 2
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Normative Cerebral Perfusion Across the Lifespan
2025 · Xinglin Zeng, Yiran Li, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
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Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals
2025 · Margaret Sunitha Selvaraj, Xihao Li, et al. · Genome biology · 2
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Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets
2025 · Yvette L. Schooneveldt, Sudip Paul, et al. · PLoS Biology · 2
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Blood and neuronal extracellular vesicle mitochondrial disruptions in schizophrenia
2025 · A. Ankeeta, Ashutosh Tripathi, et al. · Neuropsychopharmacology · 3
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