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Elucidating circuit disruptions in Alzheimer's disease

Description: Alzheimer’s disease is a progressive neurodegenerative disorder without an effective cure. Neuronal activity disruptions contribute to Alzheimer’s disease etiology and its progression. We will investigate whether macroglia play a causal role in circuit disruptions and the overall disease process.
Funding type: research
Funder scheme: R01
Start date: 2020-09-15
End date: 2025-05-31
Investigator: KSENIA V. KASTANENKA
Institution: MASSACHUSETTS GENERAL HOSPITAL
Field: Medicine
Funded outputs count: 23
Funder award ID: R01AG066171
OpenAlex ID: G791054257
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