Award

Genomic Predictors of Combat Stress Vulnerability and Resilience

Description: Post-traumatic stress disorder (PTSD) poses not only individual suffering, but also a significant burden on the US health care system, with rates to develop PTSD after combat and other trauma exposure around 10-15%. PTSD affects only some of those exposed to trauma, and vulnerability factors are poorly understood. This R01 application seeks to determine genetic contributions to and predictors of the clinical outcome of PTSD, and thus to pave the way for novel diagnostic tests and therapeutic approaches to this difficult-to-manage disorder.
Funding type: research
Funder scheme: R01
Start date: 2011-07-25
End date: 2016-04-30
Investigator: CAROLINE M NIEVERGELT
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Funded outputs count: 82
Funder award ID: R01MH093500
OpenAlex ID: G8254224117
2025 · Andrew D. Grotzinger, Josefin Werme, et al. · Nature · 130
2020 · Alicia K. Smith, Andrew Ratanatharathorn, et al. · Nature Communications · 133
2020 · Johnson, C, Phillips, T, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
2020 · the Traumatic Stress Brain Study Group, Mark W. Logue, et al. · Clinical Epigenetics · 102
2019 · Yunpeng Wang, Karen-Inge Karstoft, et al. · Journal of Affective Disorders · 16
2019 · Alicia K Smith, Andrew Ratanatharathorn, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 14
2018 · Gregory J. Tranah, Kristine Yaffe, et al. · PLoS ONE · 24
2017 · Erika J. Wolf, Hannah Maniates, et al. · Psychoneuroendocrinology · 245
2017 · Jessica Deslauriers, Dean T. Acheson, et al. · Depression and Anxiety · 23
2017 · Andrew Ratanatharathorn, Marco P. Boks, et al. · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 92
2017 · Qian Peng, Nicholas J. Schork, et al. · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 5
2016 · Beben Benyamin, Adam X. Maihofer, et al. · Human Molecular Genetics · 16
2016 · Shareefa Dalvie, Nastassja Koen, et al. · OMICS A Journal of Integrative Biology · 27
2016 · Qian Peng, Andrew Schork, et al. · PLoS Genetics · 15
2015 · Arpi Minassian, Dewleen G. Baker, et al. · JAMA Psychiatry · 1
Year
Topic