Glymphatic function in a transgenic rat model of Alzheimer's disease
Description: PUBLIC HEALTH RELEVANCE: This project will test the hypothesis that age-related decline in glymphatic clearance precedes and contributes to cognitive decline and amyloidosis in wild type rats and in a transgenic rat model of Alzheimer disease. The project will take advantage of the complementary expertise of two laboratories (MRI and optical imaging) that have successfully collaborated in the past.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2014-09-01
End date: 2019-05-31
Investigator: HELENE D BENVENISTE
Institution: UNIVERSITY OF ROCHESTER
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Funded outputs count: 137
Funder award ID: R01AG048769
OpenAlex ID: G4727317247