Mechanisms of Atherogenesis in Insulin Resistance
Description: Overall Project Narrative The marked increase in cardiovascular disease in patients with type 2 diabetes (T2D) demands an integrated cardiometabolic approach. This proposal will use this approach to explore common transcriptional and signaling mechanisms in distinct cell types that contribute to cardiometabolic disease. Through synergistic interactions among the PPG PIs, these new studies will revel important new concepts and therapeutic targets related to the integrated pathophysiology of cardiometabolic disease.
Funding type: program
Funder scheme: P01
Start date: 2007-07-15
End date: 2023-06-30
Investigator: IRA A TABAS
Institution: COLUMBIA UNIVERSITY HEALTH SCIENCES
Funded outputs count: 147
Funder award ID: P01HL087123
OpenAlex ID: G7335383603