Influence of Age on CD4 T Memory Cells
Description: PROJECT NARRATIVE The ability of the immune system to develop immunological memory is the basis for immune protection after infection or vaccination. Durability of memory varies for different vaccines or infections, in particular with increasing age. The current proposal aims at identifying the gene-regulatory networks that account for differences in the generation and longevity of memory T cells, with the ultimate goal to improve immune memory in older adults.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2013-07-01
End date: 2026-04-30
Investigator: JORG J GORONZY
Institution: MAYO CLINIC ROCHESTER
Funded outputs count: 121
Funder award ID: R01AG045779
OpenAlex ID: G3176126622