Neurobiology of Mild Cognitive Impairment in the Elderly
Description: Project Narrative This program renewal will provide a greater understanding of the pathogenesis of a critical brain network that modulates cognitive function by identifying connectome deficits during preclinical Alzheimer’s disease (AD) so early treatment strategies can be implemented. Proposed studies are relevant to the NIA mission supporting research to define the cellular and molecular biology of dementia at the earliest stage of onset, which provide targets for transcriptionally aided drug discovery at a time when no treatments exist for AD.
Funder: National Institute on Aging
Funding type: program
Funder scheme: P01
Start date: 1997-09-01
End date: 2026-03-31
Investigator: ELLIOTT JAY MUFSON (lead)
Institution: St. Joseph's Hospital and Medical Center
Funded outputs count: 481
Funder award ID: P01AG014449
OpenAlex ID: G3711302076