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Molecular and Cellular Determinants of Disease Heterogeneity in COPD

Funding type: program
Funder scheme: P50
Start date: 2007-01-12
End date: 2013-12-31
Investigator: FRANK SCIURBA
Institution: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
Funded outputs count: 118
Funder award ID: P50HL084948
OpenAlex ID: G6976887986
Enhancing atrial fibrillation risk prediction in an observational cohort of tobacco-exposed individuals: the role of pulmonary function tests, symptom scores, and imaging
2025 · Nicole Curtis, S. Mehdi Nouraie, et al. · Respiratory Research
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Lung-related risk factors associate with low bone mineral density in individuals with former tobacco exposure not meeting osteoporosis screening criteria
2025 · Xinxin Du, S. Mehdi Nouraie, et al. · Osteoporosis International · 2
STAR Has Better Discrimination for Mortality than ERS/ATS Chronic Obstructive Pulmonary Disease Severity Classification
2024 · Surya P. Bhatt, Arie Nakhmani, et al. · American Journal of Respiratory and Critical Care Medicine · 6
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Reply to Neder, to Ogata et al. , and to Graham
2023 · Surya P. Bhatt, Arie Nakhmani, et al. · American Journal of Respiratory and Critical Care Medicine · 1
Incident low muscle mass is associated with greater lung disease and lower circulating leptin in a tobacco-exposed longitudinal cohort
2023 · Richard H. Zou, S. Mehdi Nouraie, et al. · Respiratory Research · 9
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FEV1/FVC Severity Stages for Chronic Obstructive Pulmonary Disease
2023 · Surya P. Bhatt, Arie Nakhmani, et al. · American Journal of Respiratory and Critical Care Medicine · 75
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A Model to Predict Residual Volume from Forced Spirometry Measurements in Chronic Obstructive Pulmonary Disease
2022 · John W. Evankovich, S.M. Nouraie, et al. · Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · 4
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The Proteomic Profile of Interstitial Lung Abnormalities
2022 · Gisli Thor Axelsson, Gunnar Gudmundsson, et al. · American Journal of Respiratory and Critical Care Medicine · 52
Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD
2022 · Luca Giordano, Alyssa D. Gregory, et al. · Cells · 70
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Circulating 1,3-Beta-D-Glucan is Associated with Lung Function, Respiratory Symptoms, and Mediators of Matrix Degradation in Chronic Obstructive Pulmonary Disease
2022 · Matthew Gorgone, Deepti Singhvi, et al. · Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation · 4
CT pectoralis muscle area is associated with DXA lean mass and correlates with emphysema progression in a tobacco-exposed cohort
2021 · Michael Emmet O'Brien, Richard H Zou, et al. · Thorax · 28
Extracellular release of mitochondrial DNA is triggered by cigarette smoke and is detected in COPD
2021 · Luca Giordano, Alyssa D. Gregory, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD
2021 · Hilary C Strollo, Seyed M Nouraie, et al. · International Journal of COPD · 33
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HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk
2021 · Takudzwa Mkorombindo, Thi K. Tran-Nguyen, et al. · JCI Insight · 10
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The Association Between Lung Hyperinflation and Coronary Artery Disease in Smokers
2021 · Divay Chandra, Aman Gupta, et al. · CHEST Journal · 23
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Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD
2021 · Katherine A. Pratte, Jeffrey L. Curtis, et al. · Respiratory Research · 56
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Elevated plasma level of Pentraxin 3 is associated with emphysema and mortality in smokers
2021 · Yingze Zhang, John Tedrow, et al. · Thorax · 16
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Soluble Receptor for Advanced Glycation End Products (sRAGE) as a Biomarker of COPD
2020 · Katherine A. Pratte, Jeffery L. Curtis, et al. · 1
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Longitudinal associations between sleep disturbance and disease severity in patients with COPD
2020 · Faith S. Luyster, Juan Wang, et al. · Sleep Science and Practice · 8
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Glucose-Regulated Protein 78 Autoantibodies Are Associated with Carotid Atherosclerosis in Chronic Obstructive Pulmonary Disease Patients
2020 · Thi K Tran-Nguyen, Divay Chandra, et al. · ImmunoHorizons · 7
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Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers
2019 · Michael E. O’Brien, Divay Chandra, et al. · Respiratory Research · 20
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The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis
2018 · Divay Chandra, James Londino, et al. · Journal of Molecular and Cellular Cardiology · 13
Decreased serum TRAIL is associated with increased mortality in smokers with comorbid emphysema and coronary artery disease
2018 · Oluremi Ajala, Yingze Zhang, et al. · Respiratory Medicine · 13
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Mixed graphical models for integrative causal analysis with application to chronic lung disease diagnosis and prognosis
2018 · Andrew J Sedgewick, Kristina Buschur, et al. · Bioinformatics · 69
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Radiographic Emphysema, Circulating Bone Biomarkers, and Progressive Bone Mineral Density Loss in Smokers
2018 · Jessica Bon, Yingze Zhang, et al. · Annals of the American Thoracic Society · 16
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