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An organotypic model recapitulating colon cancer microenvironment and metastasis

Description: PROJECT NARRATIVE The proposed research is relevant to public health because understanding the pathogenesis of colorectal cancer metastases will result in the development of innovative preventive and therapeutic strategies. The research is relevant to the part of the NIH's mission that addresses expansion of knowledge to enhance health and to reduce illness in this context. By preventing or treating colorectal cancer metastases, this proposal will also address that part of the NIH's mission to lengthen life.
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 2017-09-25
End date: 2024-08-30
Investigator: EMINA HUI-NA HUANG
Institution: UT SOUTHWESTERN MEDICAL CENTER
Funded outputs count: 48
Funder award ID: U01CA214300
OpenAlex ID: G2539609064
2026 · Jia Yao, Yuqiu Yang, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2026 · Khalil Almotah, Uyen Tran, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2025 · Nicole C. Huning, Munir H. Buhaya, et al. · Advanced Science · 3
2024 · Paula G. Miller, Emina Huang, et al. · Biotechnology and Bioengineering · 4
2024 · Kun Xiang, Ergang Wang, et al. · Advanced Science · 15
2022 · Guanqun Meng, Wen Tang, et al. · Briefings in Bioinformatics · 15
2022 · Shree Bose, Margarida Barroso, et al. · Cancer Cell · 64
2022 · Zhaohui Wang, Matteo Boretto, et al. · Stem Cell Reports · 52
2022 · Shengli Ding, Carolyn Hsu, et al. · Cell stem cell · 228
2022 · Preetish Kadur Lakshminarasimha Murthy, Rui Xi, et al. · Developmental Cell · 31
2021 · Shree Bose, Hans Clevers, et al. · Med · 213
2021 · Qiang Huang, Aliesha Garrett, et al. · Cell stem cell · 60
2021 · Nayden Naydenov, Susana Lechuga, et al. · Cancers · 28
2021 · Samaneh K. Sarvestani, Steven Signs, et al. · Nature Communications · 113
2021 · Anders B. Dohlman, Diana Arguijo Mendoza, et al. · Cell Host & Microbe · 281
2020 · Danielle J. LaValley, Paula G. Miller, et al. · Biotechnology Progress · 21
2020 · Samaneh Kamali Sarvestani, Reece K. DeHaan, et al. · iScience · 21
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