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Developmental methylomics of childhood trauma and its health consequences

Description: PUBLIC HEALTH RELEVANCE: Adverse childhood experiences are common and their repercussions in terms of medical costs, societal cost, and psychological toll on its victims are tremendous. The goal of this project are to characterize how these experiences become "embedded" in the methylome and to identify the biologically processes that affect the long term health risks. Successful completion of this project also implies that we will have found replicable methylation biomarker signatures that could, for example, serve as diagnostic "biomarkers of damage" to guide intervention strategies.
Funding type: research
Funder scheme: R01
Start date: 2014-08-01
End date: 2021-04-30
Investigator: EDWIN VAN DEN OORD
Institution: VIRGINIA COMMONWEALTH UNIVERSITY
Funded outputs count: 25
Funder award ID: R01MH104576
OpenAlex ID: G1174653864
2025 · Mandy Meijer, Marieke Klein, et al. · European Neuropsychopharmacology · 3
2024 · Laura K. M. Han, Moji Aghajani, et al. · Psychological Medicine · 3
2023 · Shaunna L. Clark, Ellen W. McGinnis, et al. · Journal of the American Academy of Child & Adolescent Psychiatry · 9
2023 · John M. Hettema, Edwin J. C. G. van den Oord, et al. · Molecular Psychiatry · 16
2023 · Edwin JCG van den Oord, Jerry D Guintivano, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2022 · Jennifer E. Lansford, Candice L. Odgers, et al. · Psychological Assessment · 14
2022 · Charlie L. J. D. van den Oord, William E. Copeland, et al. · Molecular Psychiatry · 27
2022 · William E. Copeland, Lilly Shanahan, et al. · Journal of Child Psychology and Psychiatry · 48
2021 · Shaunna L. Clark, Robin F. Chan, et al. · Addiction Biology · 23
2021 · Anna Starnawska, Lina Bukowski, et al. · Clinical Epigenetics · 9
2021 · Edwin J. C. G. van den Oord, Lin Y. Xie, et al. · BMC Bioinformatics · 6
2021 · Robin F. Chan, William E. Copeland, et al. · Journal of Child Psychology and Psychiatry · 10
2021 · William E. Copeland, Guangyu Tong, et al. · PEDIATRICS · 7
2021 · Shaunna L. Clark, Robin Chan, et al. · Journal of the American Academy of Child & Adolescent Psychiatry · 23
2019 · Karolina A. Aberg, Robin F. Chan, et al. · Epigenetics · 38
2019 · Elizabeth J. Gifford, Lindsey Eldred Kozecke, et al. · JAMA Network Open · 69
2018 · Edwin J. C. G. van den Oord, Robin F. Chan, et al. · JAMA Psychiatry · 6
2018 · Andrey A Shabalin, Mohammad W Hattab, et al. · Bioinformatics · 56
2017 · William E. Copeland, David B. Goldston, et al. · Journal of the American Academy of Child & Adolescent Psychiatry · 104
2017 · Karolina A. Aberg, Robin F. Chan, et al. · Epigenetics · 57
2015 · William E. Copeland, Dieter Wolke, et al. · JAMA Psychiatry · 469
2015 · Andrey A Shabalin, Karolina A Aberg, et al. · Epigenomics · 23
2007 · Тюряхин Илья Николаевич · Gentiles in late Roman sources
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