Alcohol and tissue injury, from mechanisms to treatments
Description: PROJECT NARRATIVE Alcohol abuse is a leading cause of morbidity and mortality worldwide and recent data indicate that alcoholic liver disease affects over 10 million Americans. The overall goal of the Northern Ohio Alcohol Center (NOAC) is to identify specific molecular targets of ethanol-induced damage, as well as understand the complex adaptive and maladaptive responses of cells and systems to that damage. This information will enable us to target therapeutic interventions that will either slow and/or reverse the progression of disease in patients suffering from injury due to excessive alcohol consumption.
Funding type: program
Funder scheme: P50
Start date: 2016-04-15
End date: 2026-03-31
Investigator: LAURA E. NAGY
Institution: CLEVELAND CLINIC LERNER COM-CWRU
Funded outputs count: 274
Funder award ID: P50AA024333
OpenAlex ID: G9000858988