Targeting vascular dysfunction to promote lung repair and fibrosis resolution
Description: NARRATIVE Idiopathic Pulmonary Fibrosis (IPF) is a chronic, fatal disease of aging with currently limited therapeutic options. This proposal is designed to study the hypothesis that dysfunction of the pulmonary vasculature plays a critical role in the progression of lung fibrosis. Experiments of this grant will investigate the contribution of molecular abnormalities we have discovered in the lung vasculature toward our long term goal of identifying novel targets for the treatment of IPF.
Funding type: research
Funder scheme: R01
Start date: 2022-03-05
End date: 2027-02-28
Investigator: GIOVANNI LIGRESTI
Institution: BOSTON UNIVERSITY MEDICAL CAMPUS
Funded outputs count: 13
Funder award ID: R01HL158733
OpenAlex ID: G9000913182