Epigenetics of Aging and Age-Associated Diseases
Description: OVERALL NARRATIVE The epigenome is a rich target for strategies to promote healthy aging. First, approaches that promote epigenetic maintenance – chromostasis – can foster phenotypic stability and suppression of age-associated degeneration. Second, targeted epigenetic inhibitors of pro-aging cellular phenotypes, such as SASP, can also promote healthy aging. This collaborative project will explore both avenues to promote healthy aging.
Funder: National Institute on Aging
Funding type: program
Funder scheme: P01
Start date: 2008-03-15
End date: 2024-05-31
Investigator: SHELLEY L BERGER
Institution: UNIVERSITY OF PENNSYLVANIA
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 210
Funder award ID: P01AG031862
OpenAlex ID: G1524850955