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A Multivariate Mediation and Deep Learning Framework for Genome-Connectome -Substance Use Research

Description: Nicotine addiction is a worldwide public health priority and imposing health and economic burden on millions of individuals and families. This proposal seeks to identify how multiple genetic variants interactively influence the nicotine addiction through impacting brain circuitries. The improved understanding of genome-connectome pathways of addiction could lead to more effective treatment and prevention.
Funding type: grant
Funder scheme: DP1
Start date: 2019-09-01
End date: 2025-08-31
Investigator: SHUO CHEN
Institution: UNIVERSITY OF MARYLAND BALTIMORE
Funded outputs count: 68
Funder award ID: DP1DA048968
OpenAlex ID: G3060998227
2026 · Yifan Yang, Shuo Chen, et al. · Journal of Multivariate Analysis
2026 · Hwiyoung Lee, Yezhi Pan, et al. · Briefings in Bioinformatics
2026 · Tianzhou Ma, Zhenyao Ye, et al. · Neural Regeneration Research
2025 · Chixiang Chen, Shuo Chen, et al. · Journal of the American Statistical Association · 5
2025 · Li Feng, Zhenyao Ye, et al. · EBioMedicine · 11
2025 · Tong Lu, Peter Kochunov, et al. · Human Brain Mapping · 4
2025 · Hwiyoung Lee, Shuo Chen · IEEE Transactions on Pattern Analysis and Machine Intelligence · 27
2024 · Travis Canida, Hongjie Ke, et al. · Journal of the Royal Statistical Society Series C (Applied Statistics) · 4
2024 · Yezhi Pan, Chuan Bi, et al. · Nicotine & Tobacco Research · 4
2024 · Li Feng, Zhenyao Ye, et al. · American Journal of Epidemiology · 11
2024 · Neng Wang, Zhenyao Ye, et al. · Briefings in Bioinformatics · 2
2024 · Qiong Wu, Yuan Zhang, et al. · Statistics in Medicine · 4
2024 · Hwiyoung Lee, Tianzhou Ma, et al. · Briefings in Bioinformatics
2024 · Yifan Yang, Chixiang Chen, et al. · The American Statistician · 7
2024 · Chuan Bi, Thomas Nichols, et al. · Imaging Neuroscience · 4
2023 · Zhenyao Ye, Yezhi Pan, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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