Discovering how autophagy is sufficient to extend yeast replicative lifespan
Description: Narrative Aging is the cause of most human disease, including heart disease, neurodegeneration, and cancer. Chemicals, diets, and genetic interventions have been developed to extend organismal lifespan and health span, yet we have very limited knowledge of the molecular mechanisms at play. The proposed work seeks to identify ultimate molecular targets of lifespan extending interventions, that work in all species tested, during yeast replicative aging.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2023-09-01
End date: 2028-04-30
Investigator: JESSICA K TYLER
Institution: WEILL MEDICAL COLL OF CORNELL UNIV
Funded outputs count: 8
Funder award ID: R01AG079883
OpenAlex ID: G9000915517