The role of lamins in transcription and redox homeostasis
Description: PUBLIC HEALTH RELEVANCE: Mutations in the human LMNA gene cause diseases known as laminopathies that include several types of muscular dystrophy and cardiomyopathy. It is not known how these mutations cause disease. The proposed research combines the expertise of basic research scientists and clinicians and builds on their novel discoveries. The results will provide insights on disease mechanisms and identify potential therapies.
Funding type: research
Funder scheme: R21
Start date: 2013-07-01
End date: 2016-06-30
Investigator: LORI L WALLRATH
Institution: UNIVERSITY OF IOWA
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 4
Funder award ID: R21AR064894
OpenAlex ID: G2079978337