Award

AG‐007996

Funded outputs count: 69

Funder award ID: AG‐007996

OpenAlex ID: G9000268230

The microbiome mediates epiphyseal bone loss and metabolomic changes after acute joint trauma in mice

2021 · A.K. Hahn, C.W. Wallace, et al. · Osteoarthritis and Cartilage · 32

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is increased in osteoarthritis and regulates chondrocyte catabolic and anabolic activities

2020 · Loeser, R. F., Ulici, V., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill) · 3

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Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity

2020 · Kwang Il Lee, Ramya Gamini, et al. · Science Translational Medicine · 49

Histological scoring system for subchondral bone changes in murine models of joint aging and osteoarthritis

2020 · Keita Nagira, Yasunari Ikuta, et al. · Scientific Reports · 76

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FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis

2020 · Kwang Il Lee, Sungwook Choi, et al. · Proceedings of the National Academy of Sciences · 83

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Wwp2 maintains cartilage homeostasis through regulation of Adamts5

2019 · Sho Mokuda, Ryo Nakamichi, et al. · Nature Communications · 111

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Characterization of synovial fluid metabolomic phenotypes of cartilage morphological changes associated with osteoarthritis

2019 · A.K. Carlson, R.A. Rawle, et al. · Osteoarthritis and Cartilage · 122

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Faculty Opinions recommendation of Increased DNA methylation and reduced expression of transcription factors in human osteoarthritis cartilage.

2019 · David Young · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature

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Characterization of osteoarthritis phenotypes by global metabolomic profiling of human synovial fluid

2018 · Alyssa K. Carlson, Rachel A. Rawle, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1

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Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling

2018 · Yunyun Jin, Qian Cong, et al. · Development · 31

Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis

2018 · K.M. Fisch, R. Gamini, et al. · Osteoarthritis and Cartilage · 273

Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function

2018 · L.-Y. Chen, Y. Wang, et al. · Osteoarthritis and Cartilage · 127

Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes

2018 · Liang-Yu Chen, Martin Lotz, et al. · Journal of Biological Chemistry · 28

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HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles

2018 · Deokcheol Lee, Noboru Taniguchi, et al. · Scientific Reports · 19

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cGMP-dependent protein kinase-2 regulates bone mass and prevents diabetic bone loss

2018 · Ghania Ramdani, Nadine Schall, et al. · Journal of Endocrinology · 25

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Platelet-derived growth factor-coated decellularized meniscus scaffold for integrative healing of meniscus tears

2018 · Kwang Il Lee, Merissa Olmer, et al. · Acta Biomaterialia · 63

FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis

2018 · Tokio Matsuzaki, Oscar Alvarez-Garcia, et al. · Science Translational Medicine · 271

Gene expression profiles of the meniscus avascular phenotype: A guide for meniscus tissue engineering

2018 · Shawn P. Grogan, Stuart F. Duffy, et al. · Journal of Orthopaedic Research® · 26

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Transthyretin deposition promotes progression of osteoarthritis

2017 · Tokio Matsuzaki, Yukio Akasaki, et al. · Aging Cell · 33

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HMGB proteins and arthritis

2017 · Noboru Taniguchi, Yasuhiko Kawakami, et al. · Human Cell · 94

Compromised autophagy precedes meniscus degeneration and cartilage damage in mice

2017 · J.K. Meckes, B. Caramés, et al. · Osteoarthritis and Cartilage · 34

Tendons and Ligaments: Connecting Developmental Biology to Musculoskeletal Disease Pathogenesis

2017 · Hiroshi Asahara, Masafumi Inui, et al. · Journal of Bone and Mineral Research · 108

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Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells

2017 · Janneke G. C. Peeters, Nienke de Graeff, et al. · Lara D. Veeken · 16

2017 · Oscar Alvarez‐Garcia, Tokio Matsuzaki, et al. · Journal of Orthopaedic Research® · 73

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Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis

2017 · Oscar Alvarez‐Garcia, Tokio Matsuzaki, et al. · Arthritis & Rheumatology · 101