Extracellular Vesicle Analyses to Develop Aging and Resilience Biomarkers
Description: Project Narrative Extracellular vesicles (EVs) are microscopic particles, produced by all cells in the body, that circulate in the trillions in every milliliter of blood. EVs can potentially provide signatures of aging and resilience and carry proteins and other molecules that can communicate and have effects at a distance. Using large numbers of already collected precious human specimens from individuals aged 20 to over 90 years old, this project characterizes the types and role of these vesicles in aging and develops new blood biomarker tests for these vesicles to better understand mechanisms of aging and the ability to recover from stressors with aging.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2021-01-01
End date: 2026-12-31
Investigator: VIRGINIA B KRAUS
Institution: DUKE UNIVERSITY
Funded outputs count: 21
Funder award ID: R01AG070146
OpenAlex ID: G9000901667