Contributions of Hypoglycemia and Hyperglycemia to Adverse Geriatric Outcomes in NH Residents with Diabetes and Alzheimer's Disease and Related Dementias (ADRD)
Description: Project Narrative Type 2 diabetes affects nearly 1 in 3 NH residents, yet guidelines for the management of diabetes in NH are based on sparse evidence and do not adequately consider the impacts of comorbidities, especially Alzheimer's Disease and related dementias, on diabetes management. To improve the quality of care for vulnerable NH residents, it is critical to evaluate whether Alzheimer's Disease and related dementias increases the risk of developing hypoglycemia and hyperglycemia in NH residents and whether Alzheimer's Disease and related dementias alters the thresholds of hypoglycemia and hyperglycemia that can cause adverse geriatric outcomes. Our proposal will use fingerstick glucose measurements taken from routine clinical care and captured in the Veterans Affairs electronic health record system to examine the complex relationships between Alzheimer's Disease and related dementias, hypoglycemia, hyperglycemia, and adverse geriatric outcomes in NH residents.
Funder: National Institute on Aging
Funding type: career_development
Funder scheme: K01
Start date: 2021-09-01
End date: 2026-06-30
Investigator: ALEXANDRA KATHRYN LEE (lead)
Institution: University of California, San Francisco
Funded outputs count: 19
Funder award ID: K01AG073532
OpenAlex ID: G9000899976