Cytosponge cytology screening for esophageal cancer in Tanzania
Description: Esophageal squamous cell carcinoma (ESCC) is a major cause of mortality in Eastern Africa. Both ESCC and its asymptomatic precursor esophageal squamous dysplasia (ESD) are typically diagnosed by endoscopy. An alternative method, the Cytosponge, or “pill-on-a-string”, is being explored for its potential utility for early detection and etiologic research of ESCC/ESD. In this study, Dr. Mremi is set to administer Cytosponge to 500 high-risk individuals in Tanzania and assess acceptance rates. In addition, he plans to build a Cytosponge biobank that can be used to identify biomarkers and to conduct molecular studies.
Funding type: research
Funder scheme: Beginning Investigator Grant for Catalytic Research (BIG Cat)
Start date: 2023-01-01
Investigators: Alex Mremi, Alex Mremi
Institution: Kilimanjaro Christian Medical Centre
Funded outputs count: 0
Funder award ID: AACR-2023-alex-mremi
OpenAlex ID: G9000614391