Award

DK095842

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Funded outputs count: 8

Funder award ID: DK095842

OpenAlex ID: G90365767

Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A

2020 · Young-Chae Kim, Sunmi Seok, et al. · Nature Communications · 79

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

2020 · Sangwon Byun, Sunmi Seok, et al. · Nature Communications · 219

Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3

2017 · Sanghoon Kwon, Sunmi Seok, et al. · Journal of Biological Chemistry · 101

Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

2015 · Young-Chae Kim, Sangwon Byun, et al. · Genome biology · 37

FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho

2015 · Ting Fu, Young-Chae Kim, et al. · Molecular Endocrinology · 51

Farnesoid X receptor–induced lysine‐specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity

2014 · Young‐Chae Kim, Sungsoon Fang, et al. · Hepatology · 44

Sirtuin 1 Deacetylase

2013 · Jongsook Kim Kemper, Sung-E. Choi, et al. · Vitamins and hormones · 64

Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho

2012 · Ting Fu, Sung-E Choi, et al. · Proceedings of the National Academy of Sciences · 147