Mechanotransduction in Neointimal Hyperplasia Formation in Arteriovenous Grafts
Description: PUBLIC HEALTH RELEVANCE: Surgically-created blood conduits that are used for chronic hemodialysis are the lifeline for kidney failure patients, but unfortunately these conduits often fil as a result of excessive tissue growth, blocking blood flow. Currently, no clinical therapies are available to significantly prevent or treat this tissue overgrowth. The successful completion of this project will provide a sound background for the development of an innovative strategy to prevent hemodialysis blood conduit failure.
Funding type: research
Funder scheme: R01
Start date: 2014-08-07
End date: 2020-07-31
Investigator: YAN-TING E. SHIU
Institution: UNIVERSITY OF UTAH
Funded outputs count: 25
Funder award ID: R01DK100505
OpenAlex ID: G5574988582