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75N93022D00005

Funded outputs count: 109
Funder award ID: 75N93022D00005
OpenAlex ID: G970892991
Low reactogenicity and high tumour antigen expression from mRNA-LNPs with membrane-destabilizing zwitterionic lipids
2025 · Yu Zhao, Ruoxin Li, et al. · Nature Biomedical Engineering · 19
Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively
2025 · Blade A. Olson, Kathryn E. Huey-Tubman, et al. · Proceedings of the National Academy of Sciences · 3
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Overcoming impaired antigen presentation in tumor-draining lymph nodes facilitates immunotherapy
2025 · Meghan J. O’Melia, Lutz Menzel, et al. · Journal for ImmunoTherapy of Cancer · 4
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Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients
2025 · John T. Killian, R. Glenn King, et al. · Immunity · 6
Local control of T cell fate in lymph nodes safely and durably reverses myelin-driven autoimmunity
2025 · Senta M. Kapnick, Emily A. Gosselin, et al. · Proceedings of the National Academy of Sciences · 4
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The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells
2025 · Camilla Panetti, Rahel Daetwyler, et al. · Nature Immunology · 16
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Human gut bacteria produce structurally related monoglycolipids with contrasting immune functions
2025 · Ji-Sun Yoo, Da-Jung Jung, et al. · Nature Microbiology · 11
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Faithful modeling of terminal CD8+T cell dysfunction and epigenetic stabilization in vitro
2025 · Amir Yousif, Abbey A. Saadey, et al. · JCI Insight · 11
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Structural changes from wild-type define tumor-rejecting neoantigens
2025 · Anngela C Adams, Anne M Macy, et al. · Journal for ImmunoTherapy of Cancer · 4
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Mechano-ID: Proximity Labeling of Mechanically Active Receptors Reveals the Mechanome and Tags Mechanically Active Cells
2025 · Rong Ma, Mohamed Husaini Bin Abdul Rahman, et al. · Journal of the American Chemical Society · 1
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E. coli-activated cellular circuit restrains intestinal inflammatory microbiota-specific T cells and protects against colitis
2025 · Dasom V. Kim, Amanda Chen, et al. · Cell Reports · 4
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GMP Manufacturing and Characterization of the HIV Booster Immunogen HxB2.WT.Core-C4b for Germline Targeting Vaccine Strategies
2025 · Sammaiah Pallerla, Latha Kallur Siddaramaiah, et al. · Vaccines · 2
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Limited nasal IFN production contributes to delayed respiratory virus clearance and suboptimal vaccine responses
2025 · Jorna Sojati, Olivia B. Parks, et al. · JCI Insight · 5
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Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth
2025 · Domenico D’Atri, Elena Tondini, et al. · mBio · 1
Tolerance to non-inherited maternal antigen is sustained by LysM+ CD11c+ maternal microchimeric cells
2025 · Yanyan Peng, Giang Pham, et al. · Immunity · 7
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Premature thymic involution in young Foxn1lacz mutant mice causes peripheral T cell phenotypes similar to aging-induced immunosenescence
2025 · Shiyun Xiao, Seung Woo Kang, et al. · The Journal of Immunology · 6
T-cell receptor/CD28-targeted immunotherapeutics selectively drive naive T-cell expansion to generate functional HIV-specific responses
2025 · April L. Mueller, Sara Lamcaj, et al. · Journal of Virology · 1
Impact of Parabacteroides distasonis colonization on host microbiome, metabolome, immunity, and diabetes onset
2025 · Khyati Girdhar, Audrey Randall, et al. · Journal of Molecular Endocrinology · 5
Mitochondrial respiration is necessary for CD8+ T cell proliferation and cell fate
2025 · Elizabeth M. Steinert, Beatriz Furtado Bruza, et al. · Nature Immunology · 51
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Pregnancy-acquired memory CD4+ regulatory T cells improve pregnancy outcome in mice
2025 · Kristin Thiele, Christopher Urbschat, et al. · Nature Communications · 10
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Polyfunctional T follicular helper cells drive checkpoint-inhibitor diabetes and are targeted by JAK inhibitor therapy
2025 · Nicole L. Huang, Jessica G. Ortega, et al. · JCI Insight · 2
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
2025 · Etienne Humblin, Isabel Korpas, et al. · Immunity · 26
FcγRIIIa is a noncanonical costimulatory molecule for CD8 T cells
2025 · Kevin S. Kao, Nicole L. Pihlstrom, et al. · Proceedings of the National Academy of Sciences · 2
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Androgens inhibit protective CD8+ T cell responses against pre-erythrocytic malaria parasites in mice
2025 · Caroline J. Duncombe, Nilasha Sen, et al. · Nature Communications · 7
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KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression
2025 · Jonathan A. Cohen, Ashlyn A. Buzzelli, et al. · Cell Reports · 1
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