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BioIVT (United States)

Homepage: bioivt.com
Alternate names: BioIVT, BioreclamationIVT
ROR: 034rkw812
OpenAlex ID: I4402554024
The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes
2004 · A PARKINSON · Toxicology and Applied Pharmacology · 393
Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes
2003 · Ajay Madan, Richard A. Graham, et al. · Drug Metabolism and Disposition · 342
Glucuronidation Converts Gemfibrozil to a Potent, Metabolism-dependent Inhibitor of Cyp2c8: Implications for Drug-drug Interactions
2005 · Brian W. Ogilvie, Donglu Zhang, et al. · Drug Metabolism and Disposition · 331
Lysosomal Sequestration (Trapping) of Lipophilic Amine (Cationic Amphiphilic) Drugs in Immortalized Human Hepatocytes (Fa2N-4 Cells)
2013 · Faraz Kazmi, Tiffini Hensley, et al. · Drug Metabolism and Disposition · 268
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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
2021 · Hongbing Wang, Paul C. Brown, et al. · Clinical and Translational Science · 238
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A Novel, Potent, and Selective Inhibitor of Cardiac Late Sodium Current Suppresses Experimental Arrhythmias
2012 · Luiz Belardinelli, Gongxin Liu, et al. · Journal of Pharmacology and Experimental Therapeutics · 190
Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
2007 · Matthew Wortham, Maciej Czerwinski, et al. · Drug Metabolism and Disposition · 145
Pathophysiology and neurologic sequelae of cerebral malaria
2020 · Nicoline Schiess, Andres Villabona-Rueda, et al. · Malaria Journal · 129
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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
2018 · J. Gerry Kenna, Kunal S. Taskar, et al. · Clinical Pharmacology & Therapeutics · 127
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Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters
2015 · Lydia M. M Vermeer, Caleb D Isringhausen, et al. · Drug Metabolism and Disposition · 125
The Proton Pump Inhibitor, Omeprazole, but Not Lansoprazole or Pantoprazole, Is a Metabolism-Dependent Inhibitor of CYP2C19: Implications for Coadministration with Clopidogrel
2011 · Brian W. Ogilvie, Phyllis Yerino, et al. · Drug Metabolism and Disposition · 121
Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure
2016 · Sascha C. T. Nicklisch, Steven D. Rees, et al. · Science Advances · 118
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Role of Protein–Protein Interactions in Cytochrome P450-Mediated Drug Metabolism and Toxicity
2014 · Sylvie E. Kandel, Jed N. Lampe · Chemical Research in Toxicology · 108
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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
2020 · Yifeng Wang, Sumedha Gunewardena, et al. · Nature Communications · 102
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Resilience as Adaptation in Older Women
2005 · Beth Kinsel · Journal of Women & Aging · 96
Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
2020 · Abdul Basit, Naveen K. Neradugomma, et al. · Molecular Pharmaceutics · 91
System-Dependent Outcomes during the Evaluation of Drug Candidates as Inhibitors of Cytochrome P450 (CYP) and Uridine Diphosphate Glucuronosyltransferase (UGT) Enzymes: Human Hepatocytes versus Liver Microsomes versus Recombinant Enzymes
2010 · Andrew Parkinson, Faraz Kazmi, et al. · Drug Metabolism and Pharmacokinetics · 87
The Role of Acidosis in the Pathogenesis of Severe Forms of COVID-19
2021 · Yury D. Nechipurenko, Denis A. Semyonov, et al. · Biology · 80
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Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation
2021 · Md Masud Parvez, Abdul Basit, et al. · Drug Metabolism and Disposition · 79
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Dose–response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice
2011 · Ying Guo, Chad Pope, et al. · Journal of Ethnopharmacology · 78
The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
2015 · Lois J. Haupt, Faraz Kazmi, et al. · Drug Metabolism and Disposition · 71
Decreased coumarin 7-hydroxylase activities and CYP2A6 expression levels in humans caused by genetic polymorphism in CYP2A6 promoter region (CYP2A6*9)
2003 · Kazuma Kiyotani, Hiroshi Yamazaki, et al. · Pharmacogenetics · 71
An Evaluation of the Dilution Method for Identifying Metabolism-Dependent Inhibitors of Cytochrome P450 Enzymes
2011 · Andrew Parkinson, Faraz Kazmi, et al. · Drug Metabolism and Disposition · 70
The effect of fenbuconazole on cell proliferation and enzyme induction in the liver of female CD1 mice
2006 · Daland R. Juberg, Daniel R. Mudra, et al. · Toxicology and Applied Pharmacology · 65
In Vivo and in Vitro Induction of Cytochrome P450 Enzymes in Beagle Dogs
2002 · Richard A. Graham, April Downey, et al. · Drug Metabolism and Disposition · 58
Works count: 93
Works count with child institutions: 187
Citation count: 5,330
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