Novartis Institute For Tropical Diseases

Alternate name: Novartis Institute For Tropical Diseases Pte Ltd

Parent institution: Novartis (Singapore)

ROR: 00cn3vx82

OpenAlex ID: I4405253178

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition

2015 · Christopher J L Murray, Ryan M Barber, et al. · The Lancet · 2,062

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The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

2009 · Clifton E. Barry, Helena I. Boshoff, et al. · Nature Reviews Microbiology · 1,445

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

2010 · Matthias Rottmann, Case McNamara, et al. · Science · 1,222

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

2007 · Tobias Junt, E. Ashley Moseman, et al. · Nature · 874

PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release

2008 · Ramandeep Singh, Ujjini Manjunatha, et al. · Science · 638

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

2013 · Kevin Pethe, Pablo Bifani, et al. · Nature Medicine · 609

Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus

2006 · Paul Erbel, Nikolaus Schiering, et al. · Nature Structural & Molecular Biology · 598

Linezolid for Treatment of Chronic Extensively Drug-Resistant Tuberculosis

2012 · Myungsun Lee, Jongseok Lee, et al. · New England Journal of Medicine · 564

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The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

2008 · Srinivasa P. S. Rao, Sylvie Alonso, et al. · Proceedings of the National Academy of Sciences · 527

Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution

2007 · Thai Leong Yap, Ting Xu, et al. · Journal of Virology · 460

Targeting Plasmodium PI(4)K to eliminate malaria

2013 · Case W. McNamara, Marcus C. S. Lee, et al. · Nature · 441

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

2010 · Bryan K. S. Yeung, Bin Zou, et al. · Journal of Medicinal Chemistry · 435

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

2016 · Shilpi Khare, Advait S. Nagle, et al. · Nature · 419

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An adenosine nucleoside inhibitor of dengue virus

2009 · Zheng Yin, Yen-Liang Chen, et al. · Proceedings of the National Academy of Sciences · 392

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Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase

2006 · Jennifer A. McCourt, Siew Siew Pang, et al. · Proceedings of the National Academy of Sciences · 379

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Ten years of dengue drug discovery: Progress and prospects

2013 · Siew Pheng Lim, Qing-Yin Wang, et al. · Antiviral Research · 356

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

2010 · Joeli Marrero, Kyu Y. Rhee, et al. · Proceedings of the National Academy of Sciences · 354

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

2011 · Stephan Meister, David M. Plouffe, et al. · Science · 347

Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

2005 · Ujjini H. Manjunatha, Helena Boshoff, et al. · Proceedings of the National Academy of Sciences · 340

The mechanism of action of PA-824

2009 · Ujjini Manjunatha, Helena I.M. Boshoff, et al. · Communicative & Integrative Biology · 327

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

2011 · Christian G. Noble, Cheah Chen Seh, et al. · Journal of Virology · 308

A practical view of ‘druggability’

2006 · Thomas H Keller, Arkadius Pichota, et al. · Current Opinion in Chemical Biology · 305

Crystal Structure of the NS3 Protease-Helicase from Dengue Virus

2007 · Dahai Luo, Ting Xu, et al. · Journal of Virology · 304

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

2010 · Kevin Pethe, Patricia C. Sequeira, et al. · Nature Communications · 295

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Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

2017 · Tanya Paquet, Claire Le Manach, et al. · Science Translational Medicine · 287

Works count: 393

Citation count: 215,900