Get started

Japan Pharmaceutical Manufacturers Association

Homepage: jpma.or.jp
Alternate names: Nihon Seiyaku Kogyo Kyokai, ニホン セイヤク コウギョウ キョウカイ, 日本製薬工業協会
ROR: 02t1m5632
OpenAlex ID: I4405255266
Improvement of acquisition and analysis methods in multi-electrode array experiments with iPS cell-derived cardiomyocytes
2015 · Keiichi Asakura, Seiji Hayashi, et al. · Journal of Pharmacological and Toxicological Methods · 153
PDF
A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport
2003 · Hideyuki MITOMO, Ryo KATO, et al. · Biochemical Journal · 123
PDF
Spontaneous Malformations in Laboratory Animals: Frequency of External, Internal and Skeletal Malformations in Rats, Rabbits and Mice*
1987 · Haruka MORITA, Fumio ARIYUKI, et al. · Congenital Anomalies · 106
PDF
Harmonization of Animal Clinical Pathology Testing in Toxicity and Safety Studies
1996 · KURT WEINGAND, GEOFF BROWN, et al. · Toxicological Sciences · 104
QT PRODACT: In Vivo QT Assay in the Conscious Dog for Assessing the Potential for QT Interval Prolongation by Human Pharmaceuticals
2005 · Shigeki Toyoshima, Akihiro Kanno, et al. · Journal of Pharmacological Sciences · 99
PDF
Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective
2020 · Hugo M. Vargas, Michael G. Rolf, et al. · Clinical Pharmacology & Therapeutics · 94
PDF
CSAHi study: Evaluation of multi-electrode array in combination with human iPS cell-derived cardiomyocytes to predict drug-induced QT prolongation and arrhythmia — Effects of 7 reference compounds at 10 facilities
2015 · Takashi Kitaguchi, Yuta Moriyama, et al. · Journal of Pharmacological and Toxicological Methods · 90
A Collaborative Study in Japan on Optimal Treatment Period and Parameters for Detection of Male Fertility Disorders Induced by Drugs in Rats
1995 · Satoshi Takayama, Masashi Akaike, et al. · Journal of the American College of Toxicology · 88
QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation
2005 · Kentaro Ando, Toshiyasu Hombo, et al. · Journal of Pharmacological Sciences · 86
PDF
Potentials and limitations of nonclinical safety assessment for predicting clinical adverse drug reactions: correlation analysis of 142 approved drugs in Japan
2013 · Chihiro Tamaki, Takashi Nagayama, et al. · The Journal of Toxicological Sciences · 83
PDF
The Genetic Polymorphism of Drug Transporters: Functional Analysis Approaches
2004 · Toshihisa Ishikawa, Akira Tsuji, et al. · Pharmacogenomics · 76
QT PRODACT: Comparison of Non-clinical Studies for Drug-Induced Delay in Ventricular Repolarization and Their Role in Safety Evaluation in Humans
2005 · Takeshi Omata, Chieko Kasai, et al. · Journal of Pharmacological Sciences · 71
PDF
Current Status, Issues and Future Prospects of Personalized Medicine for Each Disease
2022 · Yuichi Yamamoto, Norihiro Kanayama, et al. · Journal of Personalized Medicine · 70
PDF
Delays in New Drug Applications in Japan and Industrial R&D Strategies
2009 · Y Hirai, H Kinoshita, et al. · Clinical Pharmacology & Therapeutics · 64
Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative
2016 · Kiyoshi Takasuna, Keiichi Asakura, et al. · Journal of Pharmacological and Toxicological Methods · 58
QT PRODACT: Usability of Miniature Pigs in Safety Pharmacology Studies: Assessment for Drug-Induced QT Interval Prolongation
2005 · Mayumi Kano, Tohru Toyoshi, et al. · Journal of Pharmacological Sciences · 58
PDF
QT PRODACT: A Multi-site Study of In Vitro Action Potential Assays on 21 Compounds in Isolated Guinea-Pig Papillary Muscles
2005 · Seiji Hayashi, Yoshihide Kii, et al. · Journal of Pharmacological Sciences · 46
PDF
QT PRODACT: In Vivo QT Assay in Anesthetized Dog for Detecting the Potential for QT Interval Prolongation by Human Pharmaceuticals
2005 · Hiroyuki Tashibu, Hiroyasu Miyazaki, et al. · Journal of Pharmacological Sciences · 41
PDF
CSAHi study: Detection of drug-induced ion channel/receptor responses, QT prolongation, and arrhythmia using multi-electrode arrays in combination with human induced pluripotent stem cell-derived cardiomyocytes
2017 · Takashi Kitaguchi, Yuta Moriyama, et al. · Journal of Pharmacological and Toxicological Methods · 40
QT PRODACT: Inter-facility Variability in Electrocardiographic and Hemodynamic Parameters in Conscious Dogs and Monkeys
2005 · Hiroyuki Sasaki, Noritsugu Shimizu, et al. · Journal of Pharmacological Sciences · 40
PDF
CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information
2017 · Yumiko Nozaki, Yayoi Honda, et al. · Regulatory Toxicology and Pharmacology · 37
CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability-
2016 · Yumiko Nozaki, Yayoi Honda, et al. · Regulatory Toxicology and Pharmacology · 36
QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation
2005 · Hiroyasu Miyazaki, Hiroyuki Watanabe, et al. · Journal of Pharmacological Sciences · 33
PDF
Expression and Functional Characterization of Human ABC Transporter ABCG2 Variants in Insect Cells
2003 · Toshihisa Ishikawa, Shiho Kasamatsu, et al. · Drug Metabolism and Pharmacokinetics · 31
Impact of biomarker usage on oncology drug development
2012 · K. Hayashi, S. Masuda, et al. · Journal of Clinical Pharmacy and Therapeutics · 27
Works count: 278
Citation count: 11,080
Year
Topic
Type