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Technology Research Association for Next generation natural products chemistry
Homepage:
natprodchem.jp
Alternate name:
次世代天然物化学技術研究組合
ROR:
03w0jkt32
OpenAlex ID:
I4405256183
Works
49
Awards
5
Prediction of Synthetic Accessibility Based on Commercially Available Compound Databases
2014
·
Yoshifumi Fukunishi
, Takashi Kurosawa
, et al.
·
Journal of Chemical Information and Modeling
·
106
In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives
2020
·
Kei Kudo
, Takuya Hashimoto
, et al.
·
Nature Communications
·
46
PDF
Biosynthesis of Quinolidomicin, the Largest Known Macrolide of Terrestrial Origin: Identification and Heterologous Expression of a Biosynthetic Gene Cluster over 200 kb
2018
·
Takuya Hashimoto
, Junko Hashimoto
, et al.
·
Organic Letters
·
40
myPresto/omegagene: a GPU-accelerated molecular dynamics simulator tailored for enhanced conformational sampling methods with a non-Ewald electrostatic scheme
2016
·
Kota Kasahara
, Benson Ma
, et al.
·
Biophysics and Physicobiology
·
40
PDF
Virtual‐system‐coupled adaptive umbrella sampling to compute free‐energy landscape for flexible molecular docking
2015
·
Junichi Higo
, Bhaskar Dasgupta
, et al.
·
Journal of Computational Chemistry
·
32
Structural and Molecular Basis of the Catalytic Mechanism of Geranyl Pyrophosphate C6‐Methyltransferase: Creation of an Unprecedented Farnesyl Pyrophosphate C6‐Methyltransferase
2021
·
Hayama Tsutsumi
, Yoshitaka Moriwaki
, et al.
·
Angewandte Chemie International Edition
·
28
Identification of a gene cluster for telomestatin biosynthesis and heterologous expression using a specific promoter in a clean host
2017
·
Keita Amagai
, Haruo Ikeda
, et al.
·
Scientific Reports
·
27
PDF
Prediction of Protein−compound Binding Energies from Known Activity Data: Docking‐score‐based Method and its Applications
2018
·
Yoshifumi Fukunishi
, Yasunobu Yamashita
, et al.
·
Molecular Informatics
·
26
PDF
Variation of free-energy landscape of the p53 C-terminal domain induced by acetylation: Enhanced conformational sampling
2016
·
Shinji Iida
, Tadaaki Mashimo
, et al.
·
Journal of Computational Chemistry
·
26
PDF
Sertraline, chlorprothixene, and chlorpromazine characteristically interact with the REST-binding site of the corepressor mSin3, showing medulloblastoma cell growth inhibitory activities
2018
·
Jun-ichi Kurita
, Yuuka Hirao
, et al.
·
Scientific Reports
·
25
PDF
Identification and Biosynthesis of New Acyloins from the Thermophilic Bacterium Thermosporothrix hazakensis SK20‐1T
2014
·
Jin‐Soo Park
, Noritaka Kagaya
, et al.
·
ChemBioChem
·
24
Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics
2021
·
Hiroyuki Seimiya
, Kazuo Nagasawa
, et al.
·
The Journal of Antibiotics
·
22
Quantitative Structure‐activity Relationship (QSAR) Models for Docking Score Correction
2016
·
Yoshifumi Fukunishi
, Satoshi Yamasaki
, et al.
·
Molecular Informatics
·
21
PDF
Free-energy landscape of molecular interactions between endothelin 1 and human endothelin type B receptor: fly-casting mechanism
2019
·
Junichi Higo
, Kota Kasahara
, et al.
·
Protein Engineering Design and Selection
·
19
PDF
Elastic properties of dynein motor domain obtained from all-atom molecular dynamics simulations
2016
·
Narutoshi Kamiya
, Tadaaki Mashimo
, et al.
·
Protein Engineering Design and Selection
·
19
Asp-52 in Combination with Asp-398 Plays a Critical Role in ATP Hydrolysis of Chaperonin GroEL
2014
·
Ayumi Koike-Takeshita
, Kaoru Mitsuoka
, et al.
·
Journal of Biological Chemistry
·
17
Flexible binding simulation by a novel and improved version of virtual-system coupled adaptive umbrella sampling
2016
·
Bhaskar Dasgupta
, Haruki Nakamura
, et al.
·
Chemical Physics Letters
·
15
Structural Fluctuations of Aromatic Residues in an Apo-Form Reveal Cryptic Binding Sites: Implications for Fragment-Based Drug Design
2020
·
Shinji Iida
, Hironori K. Nakamura
, et al.
·
The Journal of Physical Chemistry B
·
14
Enhancement of canonical sampling by virtual-state transitions
2017
·
Junichi Higo
, Kota Kasahara
, et al.
·
The Journal of Chemical Physics
·
14
A2B adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion
2020
·
Teita Asano
, Yuto Noda
, et al.
·
Scientific Reports
·
13
PDF
Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities
2014
·
Yasunobu Yamashita
, Ken-Ichiro Tanaka
, et al.
·
Bioorganic & Medicinal Chemistry
·
13
PDF
Actinobacterial chalkophores: the biosynthesis of hazimycins
2024
·
Kenichi Matsuda
, Hiroto Maruyama
, et al.
·
The Journal of Antibiotics
·
11
Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule
2022
·
Junichi Higo
, Kota Kasahara
, et al.
·
Scientific Reports
·
11
PDF
New azodyrecins identified by a genome mining-directed reactivity-based screening
2022
·
Atina Rizkiya Choirunnisa
, Kuga Arima
, et al.
·
Beilstein Journal of Organic Chemistry
·
11
PDF
Algibacter aquaticus sp. nov., a slightly alkaliphilic marine Flavobacterium isolated from coastal surface water
2017
·
Shu-Kuan Wong
, Sanghwa Park
, et al.
·
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
·
11
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Works count:
49
Citation count:
1,264
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