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Centre of Excellence for Long-acting Therapeutics
Homepage:
liverpool.ac.uk
Parent institution:
University of Liverpool
ROR:
03mmsx307
OpenAlex ID:
I4405260362
FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
2022
·
Teresa Brevini
, Mailis Maes
, et al.
·
Nature
·
299
PDF
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19
2021
·
Jiandong Huo
, Halina Mikolajek
, et al.
·
Nature Communications
·
147
PDF
Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse
2022
·
Frauke Seehusen
, Jordan J. Clark
, et al.
·
Viruses
·
118
PDF
Long-acting drugs and formulations for the treatment and prevention of HIV infection
2020
·
Charles Flexner
, Andrew Owen
, et al.
·
International Journal of Antimicrobial Agents
·
110
SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
2021
·
Eleanor G. Bentley
, Adam Kirby
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
91
PDF
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics
2022
·
Tom M. Quinn
, Erin E. Gaughan
, et al.
·
EBioMedicine
·
58
PDF
Impact of long-acting therapies on the global HIV epidemic
2021
·
Nomathemba C. Chandiwana
, Celicia M. Serenata
, et al.
·
AIDS
·
37
The long wait for long-acting HIV prevention and treatment formulations
2024
·
Willem Daniel Francois Venter
, Monica Gandhi
, et al.
·
The Lancet HIV
·
32
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice
2021
·
Ralf Salzer
, Jordan J. Clark
, et al.
·
FEBS Letters
·
31
PDF
Core GRADE 5: rating certainty of evidence—assessing indirectness
2025
·
Gordon Guyatt
, Alfonso Iorio
, et al.
·
BMJ
·
29
PDF
Proactive therapeutic drug monitoring of biologic drugs in adult patients with inflammatory bowel disease, inflammatory arthritis, or psoriasis: a clinical practice guideline
2024
·
Leticia Kawano-Dourado
, Eirik Klami Kristianslund
, et al.
·
BMJ
·
29
PDF
Pharmacokinetic modelling to estimate intracellular favipiravir ribofuranosyl-5′-triphosphate exposure to support posology for SARS-CoV-2
2021
·
Henry Pertinez
, Rajith K R Rajoli
, et al.
·
Journal of Antimicrobial Chemotherapy
·
29
PDF
Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19
2024
·
Jordan J. Clark
, Rebekah Penrice-Randal
, et al.
·
Viruses
·
28
Remdesivir–ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2
2022
·
Laura N. Jeffreys
, Shaun H. Pennington
, et al.
·
International Journal of Antimicrobial Agents
·
28
PDF
Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito
2023
·
Victoria A. Balta
, Deborah Stiffler
, et al.
·
Nature Communications
·
27
PDF
Toward Consensus on Correct Interpretation of Protein Binding in Plasma and Other Biological Matrices for COVID‐19 Therapeutic Development
2020
·
Marta Boffito
, David J. Back
, et al.
·
Clinical Pharmacology & Therapeutics
·
25
PDF
Safety and efficacy of four drug regimens versus standard-of-care for the treatment of symptomatic outpatients with COVID-19: A randomised, open-label, multi-arm, phase 2 clinical trial
2022
·
Nomathemba Chandiwana
, Chelsea Kruger
, et al.
·
EBioMedicine
·
20
PDF
Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells
2022
·
Carolina Q. Sacramento
, Natalia Fintelman-Rodrigues
, et al.
·
Viruses
·
20
PDF
Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection
2021
·
James J. Hobson
, Alison C. Savage
, et al.
·
Nanoscale
·
20
PDF
Nanomedicine strategies to improve therapeutic agents for the prevention and treatment of preterm birth and future directions
2023
·
Jessica Taylor
, Andrew Sharp
, et al.
·
Nanoscale Advances
·
18
PDF
Shutting the gate before the horse has bolted: is it time for a conversation about SARS-CoV-2 and antiviral drug resistance?
2021
·
Julian A. Hiscox
, Saye H. Khoo
, et al.
·
Journal of Antimicrobial Chemotherapy
·
16
PDF
Prospects for Long-Acting Treatments for Hepatitis C
2022
·
David L Thomas
, Andrew Owen
, et al.
·
Clinical Infectious Diseases
·
15
PDF
Interlaboratory comparison of endotoxin contamination assessment of nanomaterials
2024
·
Gary Hannon
, Bethany J. Heaton
, et al.
·
Nanoscale
·
14
PDF
Development of a highly sensitive bioanalytical assay for the quantification of favipiravir
2021
·
Paul Curley
, Megan Neary
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
14
PDF
Safety and pharmacokinetics of dolutegravir dispersible tablets and oral films in term neonates exposed to HIV in South Africa (PETITE-DTG study): an open-label, randomised, phase 1/2 trial
2025
·
Adrie Bekker
, Nicolas Salvadori
, et al.
·
The Lancet HIV
·
13
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Works count:
109
Citation count:
7,168
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