Get started

Pharmaco-Cell Company Ltd. (Japan)

Alternate names: Pharmaco-Cell Company, Pharmaco-Cell Company Ltd., ファーマコセル株式会社
ROR: 007kqa289
OpenAlex ID: I4405263842
A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
2008 · Shinsuke Nakagawa, Mária A. Deli, et al. · Neurochemistry International · 765
PDF
Pericytes from Brain Microvessels Strengthen the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells
2007 · Shinsuke Nakagawa, Mária A. Deli, et al. · Cellular and Molecular Neurobiology · 384
PDF
Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood–brain barrier penetration models
2012 · Éva Hellinger, Szilvia Veszelka, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 253
Factors Associated with Dengue Shock Syndrome: A Systematic Review and Meta-Analysis
2013 · Nguyen Tien Huy, Tran Van Giang, et al. · PLoS neglected tropical diseases · 248
PDF
Detachment of Brain Pericytes from the Basal Lamina is Involved in Disruption of the Blood–Brain Barrier Caused by Lipopolysaccharide-Induced Sepsis in Mice
2008 · Tsuyoshi Nishioku, Shinya Dohgu, et al. · Cellular and Molecular Neurobiology · 215
Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro
2011 · Fuyuko Takata, Shinya Dohgu, et al. · Journal of Neuroinflammation · 210
PDF
Lipopolysaccharide-Activated Microglia Induce Dysfunction of the Blood–Brain Barrier in Rat Microvascular Endothelial Cells Co-Cultured with Microglia
2009 · Noriko Sumi, Tsuyoshi Nishioku, et al. · Cellular and Molecular Neurobiology · 193
Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells
2010 · Tsuyoshi Nishioku, Junichi Matsumoto, et al. · Journal of Pharmacological Sciences · 172
PDF
Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer
2022 · Yoichi Morofuji, Shinsuke Nakagawa, et al. · Pharmaceuticals · 167
PDF
Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model
2015 · Mo Dan, Liming Xu, et al. · International Journal of Nanomedicine · 113
PDF
Tumor necrosis factor-α-stimulated brain pericytes possess a unique cytokine and chemokine release profile and enhance microglial activation
2014 · Junichi Matsumoto, Fuyuko Takata, et al. · Neuroscience Letters · 99
Role of thrombin-PAR1-PKCθ/δ axis in brain pericytes in thrombin-induced MMP-9 production and blood–brain barrier dysfunction in vitro
2017 · Takashi Machida, Shinya Dohgu, et al. · Neuroscience · 80
Brain pericytes are the most thrombin-sensitive matrix metalloproteinase-9-releasing cell type constituting the blood–brain barrier in vitro
2015 · Takashi Machida, Fuyuko Takata, et al. · Neuroscience Letters · 77
Metformin induces up-regulation of blood–brain barrier functions by activating AMP-activated protein kinase in rat brain microvascular endothelial cells
2013 · Fuyuko Takata, Shinya Dohgu, et al. · Biochemical and Biophysical Research Communications · 77
In Vitro Blood-Brain Barrier Models Using Brain Capillary Endothelial Cells Isolated from Neonatal and Adult Rats Retain Age-Related Barrier Properties
2013 · Fuyuko Takata, Shinya Dohgu, et al. · PLoS ONE · 67
PDF
Glucagon-Like Peptide-1 Strengthens the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells Under Basal and Hyperglycemia Conditions
2015 · Shuji Fukuda, Shinsuke Nakagawa, et al. · Journal of Molecular Neuroscience · 53
Initial Contact of Glioblastoma Cells with Existing Normal Brain Endothelial Cells Strengthen the Barrier Function via Fibroblast Growth Factor 2 Secretion: A New In Vitro Blood–Brain Barrier Model
2013 · Keisuke Toyoda, Kunihiko Tanaka, et al. · Cellular and Molecular Neurobiology · 53
Cilostazol Strengthens Barrier Integrity in Brain Endothelial Cells
2012 · Shoji Horai, Shinsuke Nakagawa, et al. · Cellular and Molecular Neurobiology · 48
Autocrine and paracrine up-regulation of blood–brain barrier function by plasminogen activator inhibitor-1
2010 · Shinya Dohgu, Fuyuko Takata, et al. · Microvascular Research · 48
Potential role for S100A4 in the disruption of the blood–brain barrier in collagen-induced arthritic mice, an animal model of rheumatoid arthritis
2011 · T. Nishioku, K. Furusho, et al. · Neuroscience · 45
Lysophosphatidic acid receptor, LPA6, regulates endothelial blood-brain barrier function: Implication for hepatic encephalopathy
2018 · Kayo Masago, Yasuyuki Kihara, et al. · Biochemical and Biophysical Research Communications · 44
Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model
2017 · Takashi Machida, Fuyuko Takata, et al. · PLoS ONE · 44
PDF
Lipopolysaccharide-activated microglia lower P-glycoprotein function in brain microvascular endothelial cells
2012 · Junichi Matsumoto, Shinya Dohgu, et al. · Neuroscience Letters · 38
Disruption of the blood–brain barrier in collagen-induced arthritic mice
2010 · Tsuyoshi Nishioku, Atsushi Yamauchi, et al. · Neuroscience Letters · 38
Tissue Plasminogen Activator Enhances the Hypoxia/reoxygenation-induced Impairment of the Blood–brain Barrier in a Primary Culture of Rat Brain Endothelial Cells
2008 · Takeshi Hiu, Sinsuke Nakagawa, et al. · Cellular and Molecular Neurobiology · 37
Works count: 51
Citation count: 9,710
Year
Topic
Type