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J-Pharma Co., Ltd. (Japan)
Alternate names:
J-Pharma,
J-Pharma Co., Ltd.,
ジェイファーマ株式会社
ROR:
05b2z2644
OpenAlex ID:
I4405265632
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans
2008
·
Naohiko Anzai
, Kimiyoshi Ichida
, et al.
·
Journal of Biological Chemistry
·
361
l ‐Type amino acid transporter 1 inhibitors inhibit tumor cell growth
2009
·
Koji Oda
, Noriko Hosoda
, et al.
·
Cancer Science
·
274
PDF
LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells
2013
·
Keitaro Hayashi
, Promsuk Jutabha
, et al.
·
The Journal of Immunology
·
202
First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors
2020
·
Naohiro Okano
, Daisuke Naruge
, et al.
·
Investigational New Drugs
·
179
The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)
2018
·
Yann Cormerais
, Pierre André Massard
, et al.
·
Journal of Biological Chemistry
·
177
PDF
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
2019
·
Yongchan Lee
, Pattama Wiriyasermkul
, et al.
·
Nature Structural & Molecular Biology
·
175
PDF
Human Sodium Phosphate Transporter 4 (hNPT4/SLC17A3) as a Common Renal Secretory Pathway for Drugs and Urate
2010
·
Promsuk Jutabha
, Naohiko Anzai
, et al.
·
Journal of Biological Chemistry
·
158
PDF
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia
2014
·
C Rosilio
, M Nebout
, et al.
·
Leukemia
·
128
High expression of L‐type amino‐acid transporter 1 (LAT1) in gastric carcinomas: Comparison with non‐cancerous lesions
2011
·
Masaaki Ichinoe
, Tetuo Mikami
, et al.
·
Pathology International
·
125
Metabolism and Pharmacokinetic Studies of JPH203, an L-Amino Acid Transporter 1 (LAT1) Selective Compound
2011
·
Michael F. Wempe
, Peter J. Rice
, et al.
·
Drug Metabolism and Pharmacokinetics
·
108
Strategic Plan of General Administration of Pharmaceutical Care at Ministry of Health in Saudi Arabia 2012 – 2022
2015
·
Yousef Ahmed Alomi
·
Journal of Pharma & Pharmaceutical Sciences
·
107
PDF
c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells
2012
·
KEITARO HAYASHI
, PROMSUK JUTABHA
, et al.
·
Oncology Reports
·
86
PDF
Establishment and Characterization of Mammalian Cell Lines Stably Expressing Human L-Type Amino Acid Transporters
2008
·
Emiko Morimoto
, Yoshikatsu Kanai
, et al.
·
Journal of Pharmacological Sciences
·
77
PDF
JPH203, an L-Type Amino Acid Transporter 1–Selective Compound, Induces Apoptosis of YD-38 Human Oral Cancer Cells
2014
·
Dae-Woong Yun
, Seul Ah Lee
, et al.
·
Journal of Pharmacological Sciences
·
76
PDF
Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation
2020
·
Lili Quan
, Ryuichi Ohgaki
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
75
PDF
Efficient Recovery of Lignocellulolytic Enzymes of Spent Mushroom Compost from Oyster Mushrooms, Pleurotus spp., and Potential Use in Dye Decolorization
2013
·
Seon-Hwa Lim
, Yun-Hae Lee
, et al.
·
Mycobiology
·
75
High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas
2012
·
Nobuyuki Yanagisawa
, Masaaki Ichinoe
, et al.
·
Journal of Clinical Pathology
·
75
Molecular Mechanism of Ochratoxin A Transport in the Kidney
2010
·
Naohiko Anzai
, Promsuk Jutabha
, et al.
·
Toxins
·
74
PDF
Inhibition of l -type amino acid transporter 1 activity as a new therapeutic target for cholangiocarcinoma treatment
2017
·
Supak Yothaisong
, Hasaya Dokduang
, et al.
·
Tumor Biology
·
69
Developing Potent Human Uric Acid Transporter 1 (hURAT1) Inhibitors
2011
·
Michael F. Wempe
, Promsuk Jutabha
, et al.
·
Journal of Medicinal Chemistry
·
69
Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout
2009
·
Wako Urano
, Atsuo Taniguchi
, et al.
·
Annals of the Rheumatic Diseases
·
68
Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor
2020
·
Hiroki Okanishi
, Ryuichi Ohgaki
, et al.
·
Cancer Science
·
66
PDF
LAT1‐specific inhibitor is effective against T cell‐mediated allergic skin inflammation
2019
·
Keitaro Hayashi
, Osamu Kaminuma
, et al.
·
Allergy
·
62
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone
2022
·
Ziling Ye
, Yanglei Huang
, et al.
·
Metabolic Engineering
·
61
Vascular endothelial growth factor contributes to lung vascular hyperpermeability in sepsis-associated acute lung injury
2020
·
Kengo Tomita
, Yuna Saito
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
49
PDF
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Works count:
109
Citation count:
4,365
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