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Chiome Bioscience Inc. (Japan)
Homepage:
chiome.co.jp
Alternate names:
Chiome Bioscience,
Chiome Bioscience Inc.,
株式会社カイオム・バイオサイエンス
ROR:
05bayjd51
OpenAlex ID:
I4405265634
Photoimmunotherapy targeting biliary‐pancreatic cancer with humanized anti‐TROP2 antibody
2019
·
Takashi Nishimura
, Makoto Mitsunaga
, et al.
·
Cancer Medicine
·
53
PDF
An ex vivo method for rapid generation of monoclonal antibodies (ADLib system)
2006
·
Hidetaka Seo
, Shu-ichi Hashimoto
, et al.
·
Nature Protocols
·
43
Clinical outcome of hepatocellular carcinoma can be predicted by the expression of hepatic progenitor cell markers and serum tumour markers
2018
·
Satoshi Seino
, Atsunori Tsuchiya
, et al.
·
Oncotarget
·
38
PDF
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer’s disease pathology
2021
·
Hikari Tanaka
, Kanoh Kondo
, et al.
·
Communications Biology
·
34
PDF
Anti-Semaphorin 3A neutralization monoclonal antibody prevents sepsis development in lipopolysaccharide-treated mice
2015
·
Naoya Yamashita
, Aoi Jitsuki-Takahashi
, et al.
·
International Immunology
·
29
On-chip spatiotemporal electrophysiological analysis of human stem cell derived cardiomyocytes enables quantitative assessment of proarrhythmia in drug development
2018
·
Yumiko Asahi
, Tomoyo Hamada
, et al.
·
Scientific Reports
·
23
PDF
Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion
2008
·
H. Kitao
, M. Kimura
, et al.
·
International Immunology
·
23
Delta-like 1 homolog (DLK1) as a possible therapeutic target and its application to radioimmunotherapy using 125I-labelled anti-DLK1 antibody in lung cancer models (HOT1801 and FIGHT004)
2021
·
Hironori Takagi
, Songji Zhao
, et al.
·
Lung Cancer
·
22
PDF
Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo
2022
·
Margherita Passariello
, Asami Yoshioka
, et al.
·
Journal of Experimental & Clinical Cancer Research
·
20
PDF
Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40
2008
·
Waka Lin
, Shu‐ichi Hashimoto
, et al.
·
Genes to Cells
·
18
Tri-specific tribodies targeting 5T4, CD3, and immune checkpoint drive stronger functional T-cell responses than combinations of antibody therapeutics
2025
·
Margherita Passariello
, Lorenzo Manna
, et al.
·
Cell Death Discovery
·
16
PDF
Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line
2020
·
Hidetaka Seo
, Hitomi Masuda
, et al.
·
Cellular and Molecular Immunology
·
15
PDF
Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy
2022
·
Margherita Passariello
, Asami Yoshioka
, et al.
·
International Journal of Molecular Sciences
·
12
PDF
Fast-tracking antibody maturation using a B cell-based display system
2022
·
Hitomi Masuda
, Atsushi Sawada
, et al.
·
mAbs
·
7
Analyses of Nivolumab Exposure and Clinical Safety Between 3-mg/kg Dosing and 240-mg Flat Dosing in Asian Patients with Advanced Renal Cell Carcinoma in the Real-World Clinical Setting
2020
·
Renpei Kato
, Daiki Ikarashi
, et al.
·
Translational Oncology
·
7
PDF
A Comparison of the Antitumor Efficacy of Novel Multi-Specific Tribodies with Combinations of Approved Immunomodulatory Antibodies
2023
·
Lorenzo Manna
, Rosa Rapuano Lembo
, et al.
·
Cancers
·
6
PDF
Modulation of Immunoglobulin Gene Conversion in Chicken DT40 by Enhancing Histone Acetylation, and its Application to Antibody Engineering
2007
·
Hidetaka Seo
, Takatomi Yamada
, et al.
·
Biotechnology and Genetic Engineering Reviews
·
5
PDF
A Novel Glycoengineered Humanized Antibody Targeting DLK1 Exhibits Potent Anti-Tumor Activity in DLK1-Expressing Liver Cancer Cell Xenograft Models
2024
·
Koji Nakamura
, Kota Takahashi
, et al.
·
International Journal of Molecular Sciences
·
4
PDF
Sld3CBD–Cdc45 structural insights into Cdc45 recruitment for CMG complex formation during DNA replication
2024
·
Hao Li
, Izumi Ishizaki
, et al.
·
eLife
·
4
PDF
Monoclonal antibody generation by controlled immunoglobulin gene rearrangements
2025
·
Akiho Murayama
, Shin Matsui
, et al.
·
Communications Biology
·
3
A Phase I, First‐In‐Human Study of CBA ‐1205, an Anti‐ DLK1 Monoclonal Antibody, in Patients With Advanced Solid Tumors
2025
·
Yuki Katsuya
, Masafumi Ikeda
, et al.
·
Cancer Science
·
3
PDF
Abstract 1862: Synergistic and long-lasing anti-tumor efficacy of CBA-1205, a novel glycoengineered humanized antibody targeting DLK-1, in combination with lenvatinib in human HCC xenograft models
2023
·
Koji Nakamura
, Izumi Sakaguchi
, et al.
·
Cancer Research
·
2
HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice
2011
·
Hideki Fujii
, Manabu Ato
, et al.
·
International Immunology
·
2
ADLib System for Rapid and Flexible Design of Monoclonal Antibodies
2007
·
Kunihiro OHTA
, Hidetaka SEO
·
YAKUGAKU ZASSHI
·
2
PDF
IL10RB expression in cancer cells is associated with evolutionary changes to solidify treatment resistance
2026
·
Chie Kudo-Saito
, Hiroki Ozawa
, et al.
·
BJC Reports
·
1
PDF
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Works count:
39
Citation count:
1,511
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