ImmuneSensor Therapeutics (United States)

Homepage: immunesensor.com

Alternate names: ImmuneSensor, ImmuneSensor Therapeutics, ImmuneSensor Therapeutics, Inc.

ROR: 00zm09144

OpenAlex ID: I4405267051

Tumor-targeted delivery of a STING agonist improves cancer immunotherapy

2022 · You-tong Wu, Yan Fang, et al. · Proceedings of the National Academy of Sciences · 213

The STING agonist IMSA101 enhances chimeric antigen receptor T cell function by inducing IL-18 secretion

2024 · Ugur Uslu, Lijun Sun, et al. · Nature Communications · 65

Phase 1 first-in-human dose-escalation study of IMSA101, a novel cyclic di-nucleotide STING agonist, for patients with advanced solid tumor malignancies

2025 · Jay Jacoby, Deva Mahalingam, et al. · Journal for ImmunoTherapy of Cancer · 37

cGAS inhibitor IMSB301 modifies interferon signalling in peripheral mononuclear cells of SAMHD1 genetic interferonopathy in vitro

2026 · Velda X Han, Jessica P Hayes, et al. · Clinical & Translational Immunology · 7

618 Phase 1 clinical trial evaluating the safety, biologic and anti-tumor activity of the novel STING agonist IMSA101 administered both as monotherapy and in combination with PD-(L)1 checkpoint inhibitors

2023 · Justin C Moser, Angela Alistar, et al. · Journal for ImmunoTherapy of Cancer · 6

Two phase 2A clinical trials to evaluate the safety and efficacy of IMSA101 in combination with radiotherapy and checkpoint inhibitors in oligometastatic and oligoprogressive solid tumor malignancies.

2024 · Percy Lee, Jyoti Malhotra, et al. · Journal of Clinical Oncology · 4

626 Combining an autoactivated cGAS mutant with membrane-tethered IL-12 via mRNA lipid nanoparticles promotes systemic tumor control

2026 · Anli Zhang, Yan Fang, et al. · Journal for ImmunoTherapy of Cancer

Combining an autoactivated cGAS mutant with membrane-tethered IL-12 via mRNA lipid nanoparticles promotes systemic tumor control

2026 · Anli Zhang, Yan Fang, et al. · bioRxiv (Cold Spring Harbor Laboratory)

316 STING agonist-induced IL-18 secretion enhances CAR T cell function

2023 · Ugur Uslu, Sofia Castelli, et al. · Journal for ImmunoTherapy of Cancer

Works count: 9

Citation count: 1,498