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Molecure SA (Poland)
Homepage:
molecure.com
Alternate names:
Molecure,
Molecure SA
ROR:
018bax321
OpenAlex ID:
I4405267109
Comparative analysis of RNA 3D structure prediction methods: towards enhanced modeling of RNA–ligand interactions
2024
·
Chandran Nithin
, Sebastian Kmiecik
, et al.
·
Nucleic Acids Research
·
47
Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy
2023
·
Bartlomiej Borek
, Julita Nowicka
, et al.
·
Molecular Cancer Therapeutics
·
44
PDF
OATD-02 Validates the Benefits of Pharmacological Inhibition of Arginase 1 and 2 in Cancer
2022
·
Marcin Mikołaj Grzybowski
, Paulina Seweryna Stańczak
, et al.
·
Cancers
·
44
PDF
Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity
2025
·
Marcin Mikołaj Grzybowski
, Yasemin Uçal
, et al.
·
Scientific Reports
·
34
PDF
High-Performance Liquid Chromatography Methods for Determining the Purity of Drugs with Weak UV Chromophores – A Review
2024
·
Elżbieta Sobolewska
, Magdalena Biesaga
·
Critical Reviews in Analytical Chemistry
·
25
Pathophysiology of Arginases in Cancer and Efforts in Their Pharmacological Inhibition
2024
·
Patrycja Marzęta-Assas
, Damian Jacenik
, et al.
·
International Journal of Molecular Sciences
·
23
PDF
Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1
2024
·
Wojciech Czestkowski
, Łukasz Krzemiński
, et al.
·
Journal of Medicinal Chemistry
·
22
Pharmacological Inhibition of Chitotriosidase (CHIT1) as a Novel Therapeutic Approach for Sarcoidosis
2022
·
Barbara Dymek
, Piotr Sklepkiewicz
, et al.
·
Journal of Inflammation Research
·
22
PDF
Inhibition of Macrophage-Specific CHIT1 as an Approach to Treat Airway Remodeling in Severe Asthma
2023
·
Piotr Sklepkiewicz
, Barbara Dymek
, et al.
·
International Journal of Molecular Sciences
·
17
PDF
Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion
2023
·
Anna Gzik
, Bartlomiej Borek
, et al.
·
European Journal of Medicinal Chemistry
·
13
Metabolism-driven glycosylation represents therapeutic opportunities in interstitial lung diseases
2024
·
Katarzyna Drzewicka
, Zbigniew Zasłona
·
Frontiers in Immunology
·
12
PDF
Therapeutic inhibition of USP7 promotes antitumor immune responses
2025
·
Angelika Muchowicz
, Katarzyna M Głuchowska
, et al.
·
Journal for ImmunoTherapy of Cancer
·
10
PDF
The ubiquitin-specific protease 21 is critical for cancer cell mitochondrial function and regulates proliferation and migration
2024
·
Magdalena Kulma
, Bartłomiej Hofman
, et al.
·
Journal of Biological Chemistry
·
9
PDF
The Exploitation of the Glycosylation Pattern in Asthma: How We Alter Ancestral Pathways to Develop New Treatments
2024
·
Angelika Muchowicz
, Agnieszka Bartoszewicz
, et al.
·
Biomolecules
·
8
PDF
The Role of Chitinases in Chronic Airway Inflammation Associated with Tobacco Smoke Exposure
2022
·
Natalia Przysucha
, Katarzyna Górska
, et al.
·
Cells
·
7
PDF
Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin
2025
·
Bardees M. Foda
, Annika E. Baker
, et al.
·
Frontiers in Pharmacology
·
5
PDF
Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models
2025
·
Katarzyna Drzewicka
, Katarzyna M. Głuchowska
, et al.
·
Frontiers in Immunology
·
4
PDF
717TiP An open-label, multicentre, dose-escalation, first-in-human phase I study to evaluate safety, tolerability and antineoplastic activity of OATD-02 (dual arginase 1 and arginase 2 inhibitor) in patients with selected advanced and/or metastatic solid tumors
2023
·
M.A. Dudek
, Z. Zasłona
, et al.
·
Annals of Oncology
·
4
PDF
Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity
2026
·
Jacek Chrzanowski
, Julita Nowicka
, et al.
·
Journal of Medicinal Chemistry
·
2
Minimal-tag polyamines for in situ probing of their intracellular distribution
2025
·
Zuzanna Sas
, Maciej Zakrzewski
, et al.
·
Chemical Communications
·
2
PDF
Elucidation of the Catalytic Apparatus and Mechanism of Human Chitotriosidase-1
2025
·
Dorota Niedzialek
, Grzegorz Wieczorek
, et al.
·
ACS Catalysis
·
2
PDF
HPLC with Post-Column Derivatization with Alizarin for Determination of OATD-02, an Anticancer Arginase Inhibitor in Clinical Development
2023
·
Elzbieta Sobolewska
, Magdalena Tyszkiewicz
, et al.
·
Applied Sciences
·
2
PDF
Tracking Topological and Electronic Effects on the Folding and Stability of Guanine-Deficient RNA G-Quadruplexes, Engineered with a New Computational Tool for De Novo Quadruplex Folding
2022
·
Yavuz Burak Göç
, Jakub Poziemski
, et al.
·
International Journal of Molecular Sciences
·
2
PDF
Exploring CHIT1 and YKL-40 in tuberculous pleural effusion: Insights and implications
2025
·
Natalia Przysucha
, Magdalena Paplińska-Goryca
, et al.
·
Tuberculosis
·
1
Clinical stage drugs utilizing cellular metabolism pathways
2025
·
Tristram A.J. Ryan
, Luke A.J. O'Neill
, et al.
·
Elsevier eBooks
·
1
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Works count:
35
Citation count:
4,724
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