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LigaChem Biosciences, Inc. (South Korea)
Homepage:
ligachembio.com
Alternate names:
LegoChem Biosciences,
LegoChem Biosciences, Inc.,
LigaChem Biosciences,
LigaChem Biosciences, Inc.,
LigaChemBio
ROR:
01jq2yx59
OpenAlex ID:
I4405267188
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90
2009
·
Byoung Heon Kang
, Janet Plescia
, et al.
·
Journal of Clinical Investigation
·
242
Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein–Drug Conjugates for Targeted Therapy
2015
·
Joong‐jae Lee
, Hyo‐Jung Choi
, et al.
·
Angewandte Chemie International Edition
·
87
In Vitro and In Vivo Activities of LCB01-0371, a New Oxazolidinone
2010
·
Ji-Woong Jeong
, Sung-Ji Jung
, et al.
·
Antimicrobial Agents and Chemotherapy
·
77
Activity of LCB01-0371, a Novel Oxazolidinone, against Mycobacterium abscessus
2017
·
Tae Sung Kim
, Jin Ho Choe
, et al.
·
Antimicrobial Agents and Chemotherapy
·
71
Robustaflavone, a potential non-nucleoside anti-hepatitis B agent
1998
·
David E Zembower
, Yuh-Meei Lin
, et al.
·
Antiviral Research
·
64
PDF
Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis
2021
·
Ju Sang Kim
, Yong-hyun Kim
, et al.
·
Antimicrobial Agents and Chemotherapy
·
51
Effect of Medium-chain Triglyceride (MCT) on Growth Performance, Nutrient Digestibility, Blood Characteristics in Weanling Pigs
2012
·
S. M. Hong
, J. H. Hwang
, et al.
·
Asian-Australasian Journal of Animal Sciences
·
48
PDF
In vitro anti-human immunodeficiency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A, a novel NNRTI
1998
·
Ze-Qi Xu
, Robert W. Buckheit
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
44
Development of Delpazolid for the Treatment of Tuberculosis
2020
·
Young Lag Cho
, Jichan Jang
·
Applied Sciences
·
43
PDF
Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects
2017
·
Yewon Choi
, Sang Won Lee
, et al.
·
Journal of Antimicrobial Chemotherapy
·
39
PDF
High prevalence of 6-acetylmorphine in morphine-positive oral fluid specimens
2003
·
Lance Presley
, Michael Lehrer
, et al.
·
Forensic Science International
·
39
An Elaborate New Linker System Significantly Enhances the Efficacy of an HER2‐Antibody‐Drug Conjugate against Refractory HER2‐Positive Cancers
2021
·
Seol Hwa Shin
, Yun‐Hee Park
, et al.
·
Advanced Science
·
36
SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts
2021
·
Jun Sun
, Dong Yeon Shin
, et al.
·
Nature Communications
·
33
PDF
Quantification of an Antibody-Conjugated Drug in Fat Plasma by an Affinity Capture LC-MS/MS Method for a Novel Prenyl Transferase-Mediated Site-Specific Antibody–Drug Conjugate
2020
·
Byeong ill Lee
, Min-Ho Park
, et al.
·
Molecules
·
32
PDF
Pharmacokinetics, Pharmacodynamics, and Tolerability of Single-Dose Oral LCB01-0371, a Novel Oxazolidinone with Broad-Spectrum Activity, in Healthy Volunteers
2018
·
Yong-Soon Cho
, Hyeong-Seok Lim
, et al.
·
Antimicrobial Agents and Chemotherapy
·
27
PDF
Panel strain of Klebsiella pneumoniae for beta-lactam antibiotic evaluation: their phenotypic and genotypic characterization
2017
·
Roshan Dsouza
, Naina Adren Pinto
, et al.
·
PeerJ
·
26
PDF
Efficient Single-Molecule Fluorescence Resonance Energy Transfer Analysis by Site-Specific Dual-Labeling of Protein Using an Unnatural Amino Acid
2011
·
Moon-Hyeong Seo
, Tae-Sun Lee
, et al.
·
Analytical Chemistry
·
26
In Vitro Activity of a Novel Siderophore-Cephalosporin, GT-1 and Serine-Type β-Lactamase Inhibitor, GT-055, against Escherichia coli, Klebsiella pneumoniae and Acinetobacter spp. Panel Strains
2020
·
Le Phuong Nguyen
, Naina Adren Pinto
, et al.
·
Antibiotics
·
25
PDF
Delpazolid in combination with bedaquiline, delamanid, and moxifloxacin for pulmonary tuberculosis (PanACEA-DECODE-01): a prospective, randomised, open-label, phase 2b, dose-finding trial
2025
·
Lilian Tina Minja
, Isabella van der Feltz
, et al.
·
The Lancet Infectious Diseases
·
22
PDF
A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis
2023
·
A Dierig
, M Hoelscher
, et al.
·
Trials
·
19
PDF
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I
2020
·
Seoyeon Bok
, Dong Yeon Shin
, et al.
·
Nature Communications
·
19
PDF
Antimicrobial activities of LCB10-0200, a novel siderophore cephalosporin, against the clinical isolates of Pseudomonas aeruginosa and other pathogens
2017
·
Sang-Hun Oh
, Hee-Soo Park
, et al.
·
International Journal of Antimicrobial Agents
·
19
Multiple-dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral LCB01-0371 in Healthy Male Volunteers
2018
·
Yong-Soon Cho
, Hyeong-Seok Lim
, et al.
·
Clinical Therapeutics
·
18
Bisphenol A is more potent than bisphenol S in influencing the physiological and pathological functions of lungs via inducing lung fibrosis and stimulating metastasis
2023
·
Min Heui Yoo
, A-Ram Lee
, et al.
·
Ecotoxicology and Environmental Safety
·
16
A natural compound, aristoyagonine, is identified as a potent bromodomain inhibitor by mid-throughput screening
2018
·
Young Hun Kim
, Minsung Kim
, et al.
·
Biochemical and Biophysical Research Communications
·
16
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Works count:
108
Citation count:
3,737
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