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Quotient Sciences Limited (United Kingdom)
Homepage:
quotientsciences.com
Alternate names:
Quotient Clinical Limited,
Quotient Sciences,
Quotient Sciences Limited
ROR:
03ncz2v38
OpenAlex ID:
I4405267629
Works
147
Awards
2
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial
2022
·
Johannes Levin
, Nand Sing
, et al.
·
EBioMedicine
·
96
PDF
Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis
2015
·
Paloma Benito-Gallo
, Alessandro Franceschetto
, et al.
·
European Journal of Pharmaceutics and Biopharmaceutics
·
93
PDF
Development and approval of rybelsus (oral semaglutide): ushering in a new era in peptide delivery
2021
·
Andrew L. Lewis
, Nicholas McEntee
, et al.
·
Drug Delivery and Translational Research
·
87
Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double‐Blind, Randomized, Placebo‐Controlled Phase 1 Clinical Study
2017
·
Hazel Hunt
, Kirsteen Donaldson
, et al.
·
Clinical Pharmacology in Drug Development
·
68
PDF
Netupitant PET imaging and ADME studies in humans
2013
·
Tulla Spinelli
, Selma Calcagnile
, et al.
·
The Journal of Clinical Pharmacology
·
56
Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans
2013
·
Yoshinobu Nakamaru
, Yoshiharu Hayashi
, et al.
·
Xenobiotica
·
55
Naloxone as part of a prolonged release oxycodone/naloxone combination reduces oxycodone-induced slowing of gastrointestinal transit in healthy volunteers
2011
·
Kevin Smith
, Michael Hopp
, et al.
·
Expert Opinion on Investigational Drugs
·
55
Assessment of the Mass Balance Recovery and Metabolite Profile of Avibactam in Humans and In Vitro Drug-Drug Interaction Potential
2014
·
Karthick Vishwanathan
, Stuart Mair
, et al.
·
Drug Metabolism and Disposition
·
51
Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin
2018
·
Sangeeta Raje
, Ernesto Callegari
, et al.
·
Clinical and Translational Science
·
45
PDF
Relationship Between Oral Semaglutide Tablet Erosion and Pharmacokinetics: A Pharmacoscintigraphic Study
2021
·
Tine A. Bækdal
, Morten Donsmark
, et al.
·
Clinical Pharmacology in Drug Development
·
44
Absolute Bioavailability of Osimertinib in Healthy Adults
2018
·
Karthick Vishwanathan
, Karen So
, et al.
·
Clinical Pharmacology in Drug Development
·
40
A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2 R ,6 R )‐Hydroxynorketamine in Healthy Volunteers
2024
·
Shruti M. Raja
, Jeffrey T. Guptill
, et al.
·
Clinical Pharmacology & Therapeutics
·
39
PDF
Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report
2020
·
Neil Parrott
, Sandra Suarez-Sharp
, et al.
·
Journal of Pharmaceutical Sciences
·
39
Can children swallow tablets? Outcome data from a feasibility study to assess the acceptability of different-sized placebo tablets in children (creating acceptable tablets (CAT))
2020
·
Louise Bracken
, Emma McDonough
, et al.
·
BMJ Open
·
39
PDF
A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics
2019
·
David L. Hava
, Lisa Tan
, et al.
·
British Journal of Clinical Pharmacology
·
39
Physiologically based modelling of tranexamic acid pharmacokinetics following intravenous, intramuscular, sub-cutaneous and oral administration in healthy volunteers
2021
·
Zoe Kane
, Roberto Picetti
, et al.
·
European Journal of Pharmaceutical Sciences
·
35
PDF
CC-99677, a novel, oral, selective covalent MK2 inhibitor, sustainably reduces pro-inflammatory cytokine production
2022
·
Rajula Gaur
, Kofi A. Mensah
, et al.
·
Arthritis Research & Therapy
·
34
PDF
Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects
2016
·
Angela W. Dymond
, Colin Howes
, et al.
·
Clinical Therapeutics
·
33
PDF
IV and oral fosfomycin pharmacokinetics in neonates with suspected clinical sepsis
2021
·
Zoe Kane
, Silke Gastine
, et al.
·
Journal of Antimicrobial Chemotherapy
·
30
PDF
Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor
2020
·
Samit R. Joshi
, Disala Fernando
, et al.
·
Pharmacology Research & Perspectives
·
28
PDF
Safety, Pharmacokinetics, and Pharmacodynamics of ME-401, an Oral, Potent, and Selective Inhibitor of Phosphatidylinositol 3-Kinase P110δ, Following Single Ascending Dose Administration to Healthy Volunteers
2018
·
Ofir Moreno
, Todd Butler
, et al.
·
Clinical Therapeutics
·
28
PDF
Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect
2017
·
Tamás Solymosi
, Zsolt Ötvös
, et al.
·
Cancer Chemotherapy and Pharmacology
·
26
Convection-enhanced delivery for brain malignancies: Technical parameters, formulation strategies and clinical perspectives
2025
·
Sara Jamshidi Parvar
, Cheng In Wong
, et al.
·
Advanced Drug Delivery Reviews
·
25
Disposition, metabolism and mass balance of delafloxacin in healthy human volunteers following intravenous administration
2015
·
Andrew McEwen
, Laura Lawrence
, et al.
·
Xenobiotica
·
24
Assessment of levetiracetam bioavailability from targeted sites in the human intestine using remotely activated capsules and gamma scintigraphy: Open-label, single-dose, randomized, four-way crossover study in healthy male volunteers
2010
·
Armel Stockis
, Maria Laura Sargentini-Maier
, et al.
·
Clinical Therapeutics
·
23
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Works count:
147
Citation count:
4,614
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