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Hellenic Institute for the Study of Sepsis
Homepage:
sepsis.gr
Alternate names:
Elliniko Instituto Meletis Tis Sipsis,
Ελληνικό Ινστιτούτο Μελέτης Της Σήψης
ROR:
02n4vr545
OpenAlex ID:
I4405268967
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
2021
·
Evdoxia Kyriazopoulou
, Garyfallia Poulakou
, et al.
·
Nature Medicine
·
565
PDF
The pathophysiology of sepsis and precision-medicine-based immunotherapy
2024
·
Evangelos J. Giamarellos-Bourboulis
, Anna C. Aschenbrenner
, et al.
·
Nature Immunology
·
413
PDF
LifeTime and improving European healthcare through cell-based interceptive medicine
2020
·
Nikolaus Rajewsky
, Geneviève Almouzni
, et al.
·
Nature
·
157
PDF
Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial
2025
·
Evangelos J. Giamarellos-Bourboulis
, Antigone Kotsaki
, et al.
·
JAMA
·
152
ACTIVATE-2: A Double-Blind Randomized Trial of BCG Vaccination Against COVID-19 in Individuals at Risk
2022
·
Maria Tsilika
, Esther Taks
, et al.
·
Frontiers in Immunology
·
132
PDF
A consensus immune dysregulation framework for sepsis and critical illnesses
2025
·
Andrew R. Moore
, Hong Zheng
, et al.
·
Nature Medicine
·
118
Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial
2024
·
Evangelos J Giamarellos-Bourboulis
, Athanasios Siampanos
, et al.
·
The Lancet Respiratory Medicine
·
74
Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies
2025
·
Stefanie Deinhardt-Emmer
, Benjamin G Chousterman
, et al.
·
The Lancet Respiratory Medicine
·
68
Amphotericin B in the Era of New Antifungals: Where Will It Stand?
2024
·
Karolina Akinosoglou
, Emmanouil Angelos Rigopoulos
, et al.
·
Journal of Fungi
·
62
PDF
Bloodstream infections and sepsis in Greece: over-time change of epidemiology and impact of de-escalation on final outcome
2014
·
Marina Koupetori
, Theodoros Retsas
, et al.
·
BMC Infectious Diseases
·
59
PDF
De-escalation of antimicrobial therapy in ICU settings with high prevalence of multidrug-resistant bacteria: a multicentre prospective observational cohort study in patients with sepsis or septic shock
2020
·
Christina Routsi
, Aikaterini Gkoufa
, et al.
·
Journal of Antimicrobial Chemotherapy
·
48
Biomarkers to guide sepsis management
2025
·
Vasiliki Bourika
, Evangelia-Areti Rekoumi
, et al.
·
Annals of Intensive Care
·
41
PDF
Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response
2024
·
Rachel Brandes-Leibovitz
, Anca Riza
, et al.
·
Cell Reports Medicine
·
39
Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality
2024
·
Evangelos J. Giamarellos-Bourboulis
, Massimo Antonelli
, et al.
·
EBioMedicine
·
39
Development and validation of SCOPE score: A clinical score to predict COVID-19 pneumonia progression to severe respiratory failure
2022
·
Evangelos J. Giamarellos-Bourboulis
, Garyfallia Poulakou
, et al.
·
Cell Reports Medicine
·
35
PDF
Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
2021
·
Evdoxia Kyriazopoulou
, Garyfallia Poulakou
, et al.
·
Nature Medicine
·
34
PDF
Cosmeceuticals: A Review of Clinical Studies Claiming to Contain Specific, Well-Characterized Strains of Probiotics or Postbiotics
2024
·
Ioannis M. Theodorou
, Dorothea Kapoukranidou
, et al.
·
Nutrients
·
32
Recent advances of precision immunotherapy in sepsis
2025
·
Antonios Arapis
, Dimitrios Panagiotopoulos
, et al.
·
Burns & Trauma
·
31
PDF
Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey
2025
·
Christian S. Scheer
, Evangelos J. Giamarellos-Bourboulis
, et al.
·
American Journal of Respiratory and Critical Care Medicine
·
27
Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: a subgroup analysis of the SAVE-MORE randomised trial
2022
·
Karolina Akinosoglou
, Antigone Kotsaki
, et al.
·
EClinicalMedicine
·
26
PDF
qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
2024
·
Maria Evangelia Adami
, Antigone Kotsaki
, et al.
·
Critical Care
·
24
PDF
Developing a Tool for Differentiation Between Bacterial and Viral Respiratory Infections Using Myxovirus Resistance Protein A and C-Reactive Protein
2023
·
Konstantina Iliopoulou
, Panagiotis Koufargyris
, et al.
·
Infectious Diseases and Therapy
·
20
PDF
A randomized clinical trial of lipid metabolism modulation with fenofibrate for acute coronavirus disease 2019
2022
·
Julio A. Chirinos
, Patricio Lopez-Jaramillo
, et al.
·
Nature Metabolism
·
20
PDF
Interferon gamma-induced protein 10 (IP-10) for the early prognosis of the risk for severe respiratory failure and death in COVID-19 pneumonia
2022
·
Charilaos Samaras
, Evdoxia Kyriazopoulou
, et al.
·
Cytokine
·
19
Psychobiotics Ameliorate Depression and Anxiety Status in Surgical Oncology Patients: Results from the ProDeCa Study
2025
·
Georgios Tzikos
, Eleni Chamalidou
, et al.
·
Nutrients
·
18
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Works count:
97
Citation count:
8,967
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