Get started

Integrative Structural Biology

Alternate names: Biologie structurale intégrative, UMR 9031, UMR9031
ROR: 02pab6h76
OpenAlex ID: I4405271582
Aggregate-selective removal of pathological tau by clustering-activated degraders
2024 · Jonathan Benn, Shi Cheng, et al. · Science · 82
PDF
Synthesis and Characterization of Polyhedral Silsesquioxanes Bearing Bulky Functionalized Substituents
1999 · D. P. Fasce, R. J. J. Williams, et al. · Macromolecules · 80
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
2022 · Clément Danis, Elian Dupré, et al. · Molecular Therapy · 75
PDF
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation
2020 · Sylvie Taveirne, Sigrid Wahlen, et al. · Blood · 67
PDF
Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates
2021 · François-Xavier Cantrelle, Anne Loyens, et al. · Frontiers in Molecular Neuroscience · 63
PDF
Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products
2020 · Madita Wolter, Pim de Vink, et al. · Journal of the American Chemical Society · 60
Carborane-based design of a potent vitamin D receptor agonist
2015 · Rocio Otero, Samuel Seoane, et al. · Chemical Science · 59
PDF
Fragment-based Differential Targeting of PPI Stabilizer Interfaces
2020 · Xavier Guillory, Madita Wolter, et al. · Journal of Medicinal Chemistry · 53
The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity
2023 · Carlos A. Elena-Real, Amin Sagar, et al. · Nature Structural & Molecular Biology · 51
PDF
NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment
2021 · François‐Xavier Cantrelle, Emmanuelle Boll, et al. · Angewandte Chemie International Edition · 50
Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding
2021 · Guilherme G. Moreira, François-Xavier Cantrelle, et al. · Nature Communications · 49
PDF
Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells
2021 · Marjolaine Bauzone, Mouloud Souidi, et al. · Molecular Cancer Research · 34
Phosphorylated full‐length Tau interacts with 14‐3‐3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14‐3‐3 dimer
2020 · João Filipe Neves, Olivia Petrvalská, et al. · FEBS Journal · 31
PDF
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening
2020 · Léo Faïon, Kamel Djaout, et al. · European Journal of Medicinal Chemistry · 28
PDF
BIN1 and Alzheimer’s disease: the tau connection
2025 · Pierre Dourlen, Devrim Kilinc, et al. · Trends in Neurosciences · 27
Precision proteoform design for 4R tau isoform selective templated aggregation
2024 · Andrew P. Longhini, Austin DuBose, et al. · Proceedings of the National Academy of Sciences · 27
The phosphatidylserine receptor TIM1 promotes infection of enveloped hepatitis E virus
2023 · Laura Corneillie, Irma Lemmens, et al. · Cellular and Molecular Life Sciences · 24
PDF
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses
2023 · Lucile Brier, Haitham Hassan, et al. · European Journal of Medicinal Chemistry · 24
PDF
Design of Drug‐Like Protein–Protein Interaction Stabilizers Guided By Chelation‐Controlled Bioactive Conformation Stabilization
2020 · Francesco Bosica, Sebastian A. Andrei, et al. · Chemistry - A European Journal · 24
PDF
A Novel Natural Siderophore Antibiotic Conjugate Reveals a Chemical Approach to Macromolecule Coupling
2023 · Thibault Caradec, Ernesto Anoz-Carbonell, et al. · ACS Central Science · 23
PDF
Domain 2 of Hepatitis C Virus Protein NS5A Activates Glucokinase and Induces Lipogenesis in Hepatocytes
2022 · Laure Perrin-Cocon, Cindy Kundlacz, et al. · International Journal of Molecular Sciences · 22
PDF
Hepatitis E virus RNA‐dependent RNA polymerase is involved in RNA replication and infectious particle production
2021 · Noémie Oechslin, Nathalie Da Silva, et al. · Hepatology · 22
PDF
Inhibition of tau neuronal internalization using anti-tau single domain antibodies
2025 · Clément Danis, Elian Dupré, et al. · Nature Communications · 19
PDF
Relating Conformational Equilibria to Conformer‐Specific Lipophilicities: New Opportunities in Drug Discovery
2021 · Bruno Linclau, Zhong Wang, et al. · Angewandte Chemie International Edition · 19
PDF
Probing Long‐Range Anisotropic Interactions: a General and Sign‐Sensitive Strategy to Measure 1H–1H Residual Dipolar Couplings as a Key Advance for Organic Structure Determination
2020 · Davy Sinnaeve, Julian Ilgen, et al. · Angewandte Chemie International Edition · 19
PDF
Works count: 112
Citation count: 3,920
Year
Topic
Type