Orexigen Therapeutics (United States)

Alternate name: Orexigen Therapeutics

ROR: 04cnvsy93

OpenAlex ID: I4405272581

Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

2010 · Frank L Greenway, Ken Fujioka, et al. · The Lancet · 1,092

A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity‐related risk factors (COR‐II)

2013 · Caroline M. Apovian, Louis Aronne, et al. · Obesity · 755

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Weight Loss With Naltrexone SR/Bupropion SR Combination Therapy as an Adjunct to Behavior Modification: The COR‐BMOD Trial

2010 · Thomas A. Wadden, John P. Foreyt, et al. · Obesity · 574

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Effects of Naltrexone Sustained- Release/Bupropion Sustained-Release Combination Therapy on Body Weight and Glycemic Parameters in Overweight and Obese Patients With Type 2 Diabetes

2013 · Priscilla Hollander, Alok K. Gupta, et al. · Diabetes Care · 523

Rational Design of a Combination Medication for the Treatment of Obesity

2008 · Frank L. Greenway, M.J. Whitehouse, et al. · Obesity · 354

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Comparison of Combined Bupropion and Naltrexone Therapy for Obesity with Monotherapy and Placebo

2009 · Frank L. Greenway, Eduardo Dunayevich, et al. · The Journal of Clinical Endocrinology & Metabolism · 187

Efficacy and Tolerability of an mGlu2/3 Agonist in the Treatment of Generalized Anxiety Disorder

2007 · Eduardo Dunayevich, Janelle Erickson, et al. · Neuropsychopharmacology · 181

The Role of Thermogenesis in Antipsychotic Drug‐induced Weight Gain

2008 · Aneta Stefanidis, Aaron N.A. Verty, et al. · Obesity · 105

The association between food cravings and consumption of specific foods in a laboratory taste test

2008 · Corby K. Martin, Patrick M. O’Neil, et al. · Appetite · 103

The relationship between early weight loss and weight loss at 1 year with naltrexone ER/bupropion ER combination therapy

2016 · K Fujioka, R Plodkowski, et al. · International Journal of Obesity · 90

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Early improvement in food cravings are associated with long-term weight loss success in a large clinical sample

2017 · M Dalton, G Finlayson, et al. · International Journal of Obesity · 65

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An open-label study of naltrexone and bupropion combination therapy for smoking cessation in overweight and obese subjects

2009 · Charles S. Wilcox, Nader Oskooilar, et al. · Addictive Behaviors · 61

Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity

2013 · S. R. Smith, K. Fujioka, et al. · Diabetes Obesity and Metabolism · 60

Concurrent Improvement in Both Binge Eating and Depressive Symptoms with Naltrexone/Bupropion Therapy in Overweight or Obese Subjects with Major Depressive Disorder in an Open-Label, Uncontrolled Study

2017 · Anna I. Guerdjikova, Brandon Walsh, et al. · Advances in Therapy · 53

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A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder

2008 · C Allgulander, D Nutt, et al. · Journal of Psychopharmacology · 46

Naltrexone/Bupropion Combination Therapy in Overweight or Obese Patients With Major Depressive Disorder

2013 · Susan L. McElroy, Anna I. Guerdjikova, et al. · The Primary Care Companion For CNS Disorders · 40

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Method‐of‐use study of naltrexone sustained release ( SR )/bupropion SR on body weight in individuals with obesity

2016 · Amy Halseth, Kevin Shan, et al. · Obesity · 38

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Zonisamide Prevents Olanzapine-Associated Hyperphagia, Weight Gain, and Elevated Blood Glucose in Rats

2008 · Nicholas M Wallingford, Puspha Sinnayah, et al. · Neuropsychopharmacology · 37

A Double-blind, Placebo-Controlled Study of the Impact of Galantamine on Anterograde Memory Impairment During Electroconvulsive Therapy

2013 · John D. Matthews, Caleb J. Siefert, et al. · Journal of Ect · 33

Quality of life, binge eating and sexual function in participants treated for obesity with sustained release naltrexone/bupropion

2018 · A. Halseth, K. Shan, et al. · Obesity Science & Practice · 30

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Sustained-release Naltrexone/Bupropion— A Novel Pharmacologic Approach to Obesity and Food Craving

2014 · Ken Fujioka · US Endocrinology · 22

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Patient‐reported quality of life in a randomized placebo‐controlled trial of naltrexone/bupropion for obesity

2015 · R. L. Kolotkin, S. Chen, et al. · Clinical Obesity · 21

Naltrexone/Bupropion extended release‐induced weight loss is independent of nausea in subjects without diabetes

2016 · K. Hong, K. Herrmann, et al. · Clinical Obesity · 16

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AAPS Workshop: accelerating pharmaceutical development through predictive stability approaches, April 4–5, 2016

2017 · A. L. Freed, S. T. Colgan, et al. · AAPS Open · 15

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OREX-1019: A Novel Treatment of Opioid Use Disorder and Relapse Prevention

2019 · David R. Maguire, Lisa R. Gerak, et al. · Journal of Pharmacology and Experimental Therapeutics · 12

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Works count: 31

Citation count: 11,780