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GentiBio (United States)
Homepage:
gentibio.com
Alternate names:
GentiBio,
GentiBio, Inc.
ROR:
05wwbak83
OpenAlex ID:
I4405273489
Works
31
Awards
1
Using human genetics to improve safety assessment of therapeutics
2022
·
Keren J. Carss
, Aimee M. Deaton
, et al.
·
Nature Reviews Drug Discovery
·
93
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation
2023
·
Youngho Kwon
, Heike Rösner
, et al.
·
Nature Communications
·
69
PDF
GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes
2024
·
Gene I. Uenishi
, Marko Repic
, et al.
·
JCI Insight
·
64
PDF
Harnessing regulatory T cells to establish immune tolerance
2024
·
Patrick Ho
, Ellen Cahir-McFarland
, et al.
·
Science Translational Medicine
·
59
Evaluating teratoma formation risk of pluripotent stem cell-derived cell therapy products: a consensus recommendation from the Health and Environmental Sciences Institute’s International Cell Therapy Committee
2025
·
Takeshi Watanabe
, Shin La Shu
, et al.
·
Cytotherapy
·
35
A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells
2023
·
Peter J. Cook
, Su Jung Yang
, et al.
·
Molecular Therapy
·
30
Identification of a novel PDC-E2 epitope in primary biliary cholangitis: Application for engineered Treg therapy
2024
·
Ritika Tewari
, Soo Jung Yang
, et al.
·
Journal of Autoimmunity
·
17
Current and Next Steps Toward Prediction of Human Dose for Gene Therapy Using Translational Dose‐Response Studies
2021
·
Sergey Aksenov
, John C. Roberts
, et al.
·
Clinical Pharmacology & Therapeutics
·
17
Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article
2024
·
Jan C. Klapwijk
, Alberto Del Rio Espinola
, et al.
·
Human Gene Therapy
·
9
Immunogenicity Risk Assessment of Process-Related Impurities in An Engineered T Cell Receptor Cellular Product
2024
·
Johanna Mora
, Daron Forman
, et al.
·
Journal of Pharmaceutical Sciences
·
6
Analytical Methods for In-Process Testing and Product Release
2023
·
Neil A. Haig
, Jamie E. Valeich
, et al.
·
CRC Press eBooks
·
2
An allogeneic CD19 targeted Engineered Treg approach for treating B cell mediated autoimmune diseases 2260315
2026
·
Payam Zarin
, Christopher Moore
, et al.
·
The Journal of Immunology
·
1
Preventing Fabry disease progression in a symptomatic mouse model with a recombinant adeno-associated virus (rAAV) based gene therapy
2023
·
Rizwana Islam
, Natalia Boukharov
, et al.
·
Molecular Genetics and Metabolism
·
1
Regulatory T cell function and engineering for next generation cell therapies
2026
·
Nathan W. Zammit
, Martina Sassone-Corsi
, et al.
·
Frontiers in Immunology
PDF
CD19 CAR Engineered T Regulatory Cells Promote Durable Immune Tolerance in Experimental Systemic Lupus Erythematosus
2026
·
Travis Drow
, Matteo Doglio
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
A synthetic NKG2A engager enables long-term persistence of HLA-deficient allogeneic engineered Tregs
2026
·
Tingxi Guo
, Kaya R Epstein
, et al.
·
EMBO Molecular Medicine
PDF
Comprehensive Biomarker Strategy to Monitor GNTI-122, an Engineered Regulatory T Cell Therapy in Clinical Development to Treat Type 1 Diabetes 2252996
2026
·
Gene Uenishi
, Dalia Gaddis
, et al.
·
The Journal of Immunology
ST2 enforces a ‘repair-ready’ Treg phenotype that homes to and ameliorates neuroinflammation 2260164
2026
·
Nathan Zammit
, Maegan Hoover
, et al.
·
The Journal of Immunology
Modular engineering of Tregs for the treatment of inflammatory and autoimmune diseases 2259867
2026
·
Payam Zarin
, Gene Uenishi
, et al.
·
The Journal of Immunology
GNTI-932: A Targeted, Scalable, and Hypoimmune Allogeneic Engineered Treg therapy for the treatment of Inflammatory Bowel Disease 2251383
2026
·
Martina Sassone-Corsi
, Jennifer Yam
, et al.
·
The Journal of Immunology
PDF
Allogeneic Tissue Tregs Improve Disease Outcome in Models of Acute Lung and Kidney Injury 2259889
2026
·
Payam Zarin
, Maegan Hoover
, et al.
·
The Journal of Immunology
Thought leadership in cellular starting material: A review of summary themes from the AABB cellular starting material forums of 2021–2024
2026
·
Linda S. Barnes
, Priya Baraniak
, et al.
·
Transfusion
Adoptive transfer of allogeneic murine Engineered Regulatory T cells ameliorates disease in models of ischemic stroke and acute lung injury 3688
2025
·
Payam Zarin
, Maegan Hoover
, et al.
·
The Journal of Immunology
PDF
CAR19 EngTregs offer broad capacity to modulate immune tolerance and improve safety in B and T cell mediated autoimmune disorders 3850
2025
·
Victoria L. DeVault
, Matteo Doglio
, et al.
·
The Journal of Immunology
PDF
Engineered Tissue Tregs ameliorate inflammatory and ischemic diseases 3661
2025
·
Maegan Hoover
, Priya Saikumar Lakshmi
, et al.
·
The Journal of Immunology
PDF
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Works count:
31
Citation count:
1,282
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