Pearl Therapeutics (United States)

Alternate names: Pearl Therapeutics, Pearl Therapeutics, Inc.

Parent institution: AstraZeneca (United States)

ROR: 035cg8y37

OpenAlex ID: I4405280598

Pharmaceutical Particle Engineering via Spray Drying

2007 · Reinhard Vehring · Pharmaceutical Research · 1,757

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Improvement of the dispersibility of spray-dried budesonide powders using leucine in an ethanol–water cosolvent system

2012 · Mohammed A. Boraey, Susan Hoe, et al. · Powder Technology · 131

Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD

2016 · Fernando J. Martinez, Klaus F. Rabe, et al. · CHEST Journal · 105

Cosuspensions of Microcrystals and Engineered Microparticles for Uniform and Efficient Delivery of Respiratory Therapeutics from Pressurized Metered Dose Inhalers

2012 · Reinhard Vehring, David Lechuga-Ballesteros, et al. · Langmuir · 94

Long-term safety and efficacy of glycopyrrolate/formoterol metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with chronic obstructive pulmonary disease

2017 · Nicola A. Hanania, Donald P. Tashkin, et al. · Respiratory Medicine · 70

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Drug Delivery from an Innovative LAMA/LABA Co-suspension Delivery Technology Fixed-Dose Combination MDI: Evidence of Consistency, Robustness, and Reliability

2017 · Amber Doty, Jon Schroeder, et al. · AAPS PharmSciTech · 59

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Baseline Symptom Score Impact on Benefits of Glycopyrrolate/Formoterol Metered Dose Inhaler in COPD

2017 · Fernando J. Martinez, Leonardo M. Fabbri, et al. · CHEST Journal · 58

Novel Cosuspension Metered-Dose Inhalers for the Combination Therapy of Chronic Obstructive Pulmonary Disease and Asthma

2011 · David Lechuga-Ballesteros, Brian Noga, et al. · Future Medicinal Chemistry · 57

Equivalence Considerations for Orally Inhaled Products for Local Action—ISAM/IPAC-RS European Workshop Report

2012 · Carole Evans, David Cipolla, et al. · Journal of Aerosol Medicine and Pulmonary Drug Delivery · 56

Gamma scintigraphic pulmonary deposition study of glycopyrronium/formoterol metered dose inhaler formulated using co-suspension delivery technology

2017 · Glyn Taylor, Simon Warren, et al. · European Journal of Pharmaceutical Sciences · 52

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Low-frequency shift dispersive Raman spectroscopy for the analysis of respirable dosage forms

2014 · Hui Wang, Mohammed A. Boraey, et al. · International Journal of Pharmaceutics · 48

Co-suspension delivery technology in pressurized metered-dose inhalers for multi-drug dosing in the treatment of respiratory diseases

2017 · Gary T. Ferguson, Anthony J. Hickey, et al. · Respiratory Medicine · 46

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A randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 µg compared with tiotropium 18 µg in patients with COPD

2016 · Gregory Feldman, François Maltais, et al. · International Journal of COPD · 46

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Macro-Raman spectroscopy for bulk composition and homogeneity analysis of multi-component pharmaceutical powders

2017 · Hui Wang, David Barona, et al. · Journal of Pharmaceutical and Biomedical Analysis · 42

The use of modeling in spray drying of emulsions and suspensions accelerates formulation and process development

2010 · James W. Ivey, Reinhard Vehring · Computers & Chemical Engineering · 39

A randomized, parallel-group study to evaluate the efficacy of umeclidinium/vilanterol 62.5/25 µg on health-related quality of life in patients with COPD

2016 · Thomas M Siler, Alison Donald, et al. · International Journal of COPD · 28

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A randomized, seven-day study to assess the efficacy and safety of a glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler using novel Co-Suspension™ Delivery Technology in patients with moderate-to-very severe chronic obstructive pulmonary disease

2017 · Colin Reisner, Leonardo M. Fabbri, et al. · Respiratory Research · 24

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Randomized study of the safety, pharmacokinetics, and bronchodilatory efficacy of a proprietary glycopyrronium metered-dose inhaler in study patients with chronic obstructive pulmonary disease

2014 · Stephen Rennard, Charles Fogarty, et al. · BMC Pulmonary Medicine · 24

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A Two One-Sided Parametric Tolerance Interval Test for Control of Delivered Dose Uniformity. Part 1—Characterization of FDA Proposed Test

2009 · Steven Novick, David Christopher, et al. · AAPS PharmSciTech · 24

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A multicenter, randomized, double-blind dose-ranging study of glycopyrrolate/formoterol fumarate fixed-dose combination metered dose inhaler compared to the monocomponents and open-label tiotropium dry powder inhaler in patients with moderate-to-severe COPD

2016 · Donald P. Tashkin, Fernando J. Martinez, et al. · Respiratory Medicine · 21

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Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD

2016 · Leonardo M. Fabbri, Edward M. Kerwin, et al. · Respiratory Research · 17

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24-h bronchodilation and inspiratory capacity improvements with glycopyrrolate/formoterol fumarate via co-suspension delivery technology in COPD

2017 · Colin Reisner, Gregory Gottschlich, et al. · Respiratory Research · 16

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Fixed combination of glycopyrrolate and formoterol MDI (GFF-MDI) demonstrates superior inspiratory capacity (IC) compared to tiotropium DPI (Tio) following 7 days dosing, in a randomized, double-blind, placebo-controlled phase 2b study in patients with COPD

2011 · Colin Reisner, Earl St. Rose, et al. · European Respiratory Journal · 13

Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers

2018 · Jeffry D. Schroeter, Poonam Sheth, et al. · AAPS PharmSciTech · 12

Quantitative Macro-Raman Spectroscopy on Microparticle-Based Pharmaceutical Dosage Forms

2015 · Hui Wang, Lisa Williams, et al. · Applied Spectroscopy · 12

Works count: 55

Citation count: 6,139