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Tarveda Therapeutics (United States)
Alternate names:
Blend Therapeutics,
Tarveda Therapeutics,
Tarveda Therapeutics, Inc.
ROR:
03g5npx26
OpenAlex ID:
I4405280832
Cancer nanomedicine: progress, challenges and opportunities
2016
·
Jinjun Shi
, Philip W. Kantoff
, et al.
·
Nature reviews. Cancer
·
6,089
PDF
Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer
2019
·
Kerry A. Whalen
, Brian H. White
, et al.
·
Molecular Cancer Therapeutics
·
80
Correlation of Inhibitory Effects of Polymers on Indomethacin Precipitation in Solution and Amorphous Solid Crystallization Based on Molecular Interaction
2013
·
Harsh Chauhan
, Anuj Kuldipkumar
, et al.
·
Pharmaceutical Research
·
75
Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo
2019
·
Brian H. White
, Kerry Whalen
, et al.
·
Journal of Medicinal Chemistry
·
58
Pen-866, a miniature drug conjugate of a heat shock protein 90 (HSP90) ligand linked to SN38 for patients with advanced solid malignancies: Phase I and expansion cohort results.
2020
·
Gerald Steven Falchook
, Johanna C. Bendell
, et al.
·
Journal of Clinical Oncology
·
32
First in human phase 1/2a study of PEN-221 somatostatin analog (SSA)-DM1 conjugate for patients (PTS) with advanced neuroendocrine tumor (NET) or small cell lung cancer (SCLC): Phase 1 results.
2018
·
Melissa Lynne Johnson
, Tim Meyer
, et al.
·
Journal of Clinical Oncology
·
26
The safety and efficacy of PEN-221 somatostatin analog (SSA)-DM1 conjugate in patients (PTS) with advanced GI mid-gut neuroendocrine tumor (NET): Phase 2 results.
2021
·
Daniel M. Halperin
, Melissa Lynne Johnson
, et al.
·
Journal of Clinical Oncology
·
20
Simple Method Provides Resolution of Albumin, Lipoprotein, Free Fraction, and Chylomicron To Enhance the Utility of Protein Binding Assays
2015
·
Adam H. Brockman
, Haley R. Oller
, et al.
·
Journal of Medicinal Chemistry
·
13
First in human phase I/IIa study of PEN-866, a heat shock protein 90 (HSP90) ligand – SN38 conjugate for patients with advanced solid tumours: Phase I results
2019
·
J.C. Bendell
, G. Falchook
, et al.
·
Annals of Oncology
·
11
Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors
2020
·
Samantha Perino
, Benoit Moreau
, et al.
·
Molecular Cancer Therapeutics
·
10
PDF
Abstract CT156: Characterization of PEN-866, a Heat Shock Protein 90 (HSP90) binding conjugate of SN-38, in patient plasma and tumors from the first in human study
2020
·
Anish Thomas
, Kristina Kriksciukaite
, et al.
·
Cancer Research
·
6
Abstract 4484: BTP-114: An albumin binding cisplatin prodrug with improved and sustained tumor growth inhibition
2015
·
Benoit Moreau
, Rossitza Alargova
, et al.
·
Cancer Research
·
5
Abstract 3674: Pentarins: Improved tumor targeting through nanoparticle encapsulation of miniaturized biologic drug conjugates
2015
·
Mark T. Bilodeau
, Rajesh Shinde
, et al.
·
Cancer Research
·
5
Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat
2018
·
Jennifer L. Dumouchel
, Upendra A. Argikar
, et al.
·
Drug Metabolism Letters
·
4
Abstract 39: Discovery of PEN-221, an SSTR2-targeting maytansinoid conjugate with potent activity in vitro and in vivo
2017
·
Brian H. White
, Patrick Bazinet
, et al.
·
Cancer Research
·
2
Abstract 4328: Epigenetic modulation of SSTR2 expression provides the potential to broaden PEN-221 treatment population
2019
·
Samantha Perino
, James Quinn
, et al.
·
Cancer Research
·
1
Simple Method Provides Resolution of Albumin, Lipoprotein, Free Fraction, and Chylomicron to Enhance the Utility of Protein Binding Assays
2015
·
Adam Brockman
, Haley Oller
, et al.
·
The FASEB Journal
·
1
Abstract 4328: Epigenetic modulation of SSTR2 expression provides the potential to broaden PEN-221 treatment population
2019
·
Samantha Perino
, James Quinn
, et al.
·
Molecular and Cellular Biology / Genetics
Abstract 5806: Combination of the miniature drug conjugate PEN-866 with PARP inhibitors as a rational approach to overcoming limitations of PARP inhibitor monotherapy
2018
·
Samantha Perino
, James M. Quinn
, et al.
·
Cancer Research
In vitro investigation of catabolism and metabolism of antibody drug conjugates (ADCS)
2018
·
Mithat Gunduz
, Amanda L. Cirello
, et al.
·
Drug Metabolism and Pharmacokinetics
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Works count:
20
Citation count:
9,733
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