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OrganoTherapeutics SARL (Luxembourg)

Alternate names: OrganoTherapeutics, OrganoTherapeutics GmbH, OrganoTherapeutics SARL
ROR: 03f66sm36
OpenAlex ID: I4405284389
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state
2021 · Semra Smajić, Cesar A. Prada-Medina, et al. · Brain · 649
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Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
2022 · Sonia Sabate‐Soler, Sarah Louise Nickels, et al. · Glia · 203
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Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐Cyclodextrin Treatment
2021 · Javier Jarazo, Kyriaki Barmpa, et al. · Movement Disorders · 100
Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids
2023 · Isabel Rosety, Alise Zagare, et al. · npj Parkinson s Disease · 42
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PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons
2021 · Sarah J. Brown, Ibrahim Boussaad, et al. · Scientific Reports · 42
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Synaptic decline precedes dopaminergic neuronal loss in human midbrain organoids harboring a triplication of the SNCA gene
2021 · Jennifer Modamio, Claudia Saraiva, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 16
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Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication
2026 · Catarina Serra-Almeida, Javier Jarazo, et al. · npj Parkinson s Disease · 4
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Generalising from conventional pipelines using deep learning in high-throughput screening workflows
2022 · Beatriz Garcia Santa Cruz, Jan Slter, et al. · Scientific Reports · 4
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Released mitochondrial DNA and neurofilament light chain as Parkinson’s disease phenotypes in patient-specific midbrain assembloids
2025 · Sonia Sabate-Soler, Isabel Rosety, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
Brain organoids in Parkinson’s disease drug development: Human-specific models for translational discovery
2026 · Alise Zagare, Javier Jarazo, et al. · Drug Discovery Today · 1
SARS‐CoV‐2 Infection Induces Dopaminergic Neuronal Loss in Midbrain Organoids
2026 · Javier Jarazo, Eveline Santos da Silva, et al. · Journal of Neurochemistry · 1
SARS-CoV-2 infection induces dopaminergic neuronal loss in midbrain organoids during short and prolonged cultures
2023 · Javier Jarazo, Eveline Santos da Silva, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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LRRK2-G2019S impairs astrocyte differentiation and triggers a senescence-like phenotype in Parkinson’s disease models
2026 · Lisa Smits, Stefano Magni, et al. · npj Parkinson s Disease
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Replicative senescence of neural progenitors induces astrocyte senescence in 2D cultures and human midbrain organoids
2026 · Virginia Cora, Daniele Ferrante, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Mitochondrial DNA and neurofilament release as Parkinson’s phenotypes in midbrain organoids
2026 · Sonia Sabate-Soler, Isabel Rosety, et al. · Academia Neuroscience and Brain Research
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PINK1 regulates cholesterol homeostasis via SCAP phosphorylation in human dopaminergic neurons
2025 · Karan Sharma, Claudia Cavarischia-Rega, et al. · bioRxiv (Cold Spring Harbor Laboratory)
DJ-1 mediates regulation of metabolism and immune response in Parkinson’s disease astrocytes and Glioblastoma cells
2024 · Pauline Mencke, Jochen Ohnmacht, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Works count: 17
Citation count: 1,814
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