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Trans Chromosomics, Inc. (Japan)
Homepage:
trans-chromo.com
Alternate names:
Trans Chromosomics Inc.,
Trans Chromosomics, Inc.,
株式会社Trans Chromosomics
ROR:
05kr5ex05
OpenAlex ID:
I4405285521
A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site
2021
·
Taishi Onodera
, Shunsuke Kita
, et al.
·
Immunity
·
62
A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features
2022
·
Yasuhiro Kazuki
, Feng J. Gao
, et al.
·
The American Journal of Human Genetics
·
40
PDF
Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci
2022
·
Hiroyuki Satofuka
, Satoshi Abe
, et al.
·
Nature Communications
·
33
PDF
Transchromosomic technology for genomically humanized animals
2020
·
Takashi Moriwaki
, Satoshi Abe
, et al.
·
Experimental Cell Research
·
33
Current advances in microcell-mediated chromosome transfer technology and its applications
2020
·
Teruhiko Suzuki
, Yasuhiro Kazuki
, et al.
·
Experimental Cell Research
·
25
Human and mouse artificial chromosome technologies for studies of pharmacokinetics and toxicokinetics
2018
·
Daisuke Satoh
, Satoshi Abe
, et al.
·
Drug Metabolism and Pharmacokinetics
·
25
PDF
Quantitative prediction of P‐glycoprotein‐mediated drug–drug interactions and intestinal absorption using humanized mice
2021
·
Taiji Miyake
, Haruka Tsutsui
, et al.
·
British Journal of Pharmacology
·
22
Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models
2017
·
Narumi Uno
, Satoshi Abe
, et al.
·
Journal of Human Genetics
·
21
PDF
Development of Caco-2 cells expressing four CYPs via a mammalian artificial chromosome
2020
·
Yumi Ohta
, Kanako Kazuki
, et al.
·
BMC Biotechnology
·
20
PDF
Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome
2023
·
Anna J. Moyer
, Fabian-Xosé Fernandez
, et al.
·
Disease Models & Mechanisms
·
18
PDF
Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate
2023
·
Hiroyuki Satofuka
, Yayan Wang
, et al.
·
Scientific Reports
·
14
PDF
Establishment of an antibody specific for AMIGO2 improves immunohistochemical evaluation of liver metastases and clinical outcomes in patients with colorectal cancer
2022
·
Keisuke Goto
, Mitsuhiko Osaki
, et al.
·
Diagnostic Pathology
·
14
PDF
Increased propensity for infantile spasms and altered neocortical excitation-inhibition balance in a mouse model of down syndrome carrying human chromosome 21
2023
·
Li-Rong Shao
, Feng Gao
, et al.
·
Neurobiology of Disease
·
13
Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
2021
·
Satoshi Abe
, Kazuhisa Honma
, et al.
·
Scientific Reports
·
12
PDF
Rejuvenation of human mesenchymal stem cells using a nonintegrative and conditionally removable Sendai virus vector
2024
·
Mitsuo Oshimura
, Toshiaki Tabata
, et al.
·
Scientific Reports
·
10
PDF
Stunning pharmacological properties of DS-5141b, an antisense oligonucleotide consisting of 2'-O,4'-C-ethylene-bridged nucleic acids and 2'-O-methyl RNA, on dystrophin mRNA exon skipping
2017
·
K. Takaishi
, M. Kakuta
, et al.
·
Neuromuscular Disorders
·
7
Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model
2023
·
Yosuke Hiramuki
, Satoshi Abe
, et al.
·
Scientific Reports
·
5
PDF
Human artificial chromosome carrying R-spondin1 and IL-22 expression cassettes in rejuvenated MSCs enhances therapeutic efficacy in ulcerative colitis model mice
2024
·
Yayan Wang
, Kanako Kazuki
, et al.
·
Biomedicine & Pharmacotherapy
·
4
Developing a workflow for the isolation of hybridoma cells producing fully human antigen-specific antibodies using a surface IgG detection method
2024
·
Hiroyuki Satofuka
, Yayan Wang
, et al.
·
Scientific Reports
·
4
PDF
Generation of transchromosomic mice harboring HLA-A/B/C and human B2M via mouse artificial chromosome and triple BAC integration
2025
·
Nanami Kishima
, Takashi Moriwaki
, et al.
·
Scientific Reports
·
2
PDF
Rejuvenation of mesenchymal stromal cells via partial reprogramming enables scalable generation of transcriptionally diverse MSC libraries
2026
·
Haochen Tu
, Aoi Hosaka
, et al.
·
Stem Cell Research & Therapy
·
1
Structural and virological identification of neutralizing antibody footprint provides insights into therapeutic antibody design against SARS-CoV-2 variants
2025
·
Yuki Anraku
, Shunsuke Kita
, et al.
·
Communications Biology
·
1
Partial Reprogramming Uncouples Cellular Identity from Cellular Aging in Mesenchymal Stromal Cells
2026
·
Mitsuo Oshimura
·
International Journal of Stem Cells and Medicine
PDF
8C7 : A Fully Human Anti‐ PTGFRN Monoclonal Antibody‐Drug Conjugate Inhibiting Tumour Growth of Mesothelioma and Paediatric Medulloblastoma Cell Lines
2025
·
Jorge Marquez
, Jianping Dong
, et al.
·
Journal of Cellular and Molecular Medicine
PDF
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Works count:
24
Citation count:
923
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