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Preliminary toxicological study of Sylgard 184 curing agent

Year: 1978
Type: report
Abstract: The acute oral LD/sub 50//sup 30/ values for mice and rats receiving Sylgard 184 curing agent were greater than 5 g/kg. According to classical guidelines, the compound would be considered slightly toxic or practically nontoxic in both species. Skin application studies in the rabbit demonstrated the compound to be mildly irritating. Eye irritation studies, also in the rabbit, showed that Sylgard 184 curing agent was a mild but transitory irritant. The sensitization study in guinea pigs did not show the resin to be deleterious.
Authors: D Smith, J London, G Drake, R Thomas
Language: English
Subfield: Dermatology
Field: Medicine
Open Access status: green
OpenAlex ID: W102853650
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