Enhancing Arden Syntax for Clinical Trial Eligibility Criteria
Year: 1999
Type: article
Abstract: Background. We have designed a general expression syntax based on the Arden Syntax' for the purpose of representing eligibility criteria in clinical trial protocols. We are developing an application2 that finds clinical trials for which a patient is eligible. The system compares the information entered by the user against each of the eligibility criteria in a database of clinical trials and returns a rank-ordered list of matches. The goal of this project was to design a syntax that would allow us to accurately represent eligibility criteria in breast cancer clinical trial protocols. Most existing Arden applications do not address the more complex needs required to represent clinical trial eligibility criteria, such as representing medical problems and treatment data. Because of these requirements, we found it necessary to make extensions to Arden for our application. This enhanced Arden-based syntax could be adopted as the standard for representing logic for the GuideLine Interchange Format (GLIF), an object-based guideline representation language designed by the InterMED collaboratory3. Approach. Below, we briefly describe the enhancements made to the Arden Syntax for our application.
Source: PubMed Central
Language: English
Subfield: Health Information Management
Field: Health Professions
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W104974432